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直肠癌腹腔镜切除术对机体NK细胞功能的影响 被引量:1

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摘要 目的探讨直肠癌腹腔镜切除术对外周NK细胞的影响。方法纳入2012年1月至2013年12月在防城港市中医医院收治直肠癌患者45例,随机分为腹腔镜手术组23例,开腹手术组22例,分别在术前1天,术后第3天,术后第7天采集外周静脉血,运用流式细胞技术检测外周NK细胞,MTT法检测NK细胞杀伤活性。结果术后第3天、第7天腹腔镜手术组患者外周NK细胞均比开腹手术组患者明显增多,差异具有统计学意义(P<0.05),不同时间点NK细胞杀伤活性差异无统计学意义(P>0.05)。结论直肠癌腹腔镜切除术对外周NK细胞影响较小,不同手术方式对NK细胞杀伤活性无影响。
出处 《结直肠肛门外科》 2014年第5期343-345,共3页 Journal of Colorectal & Anal Surgery
基金 防城港市科学研究与技术开发计划课题(防科攻1102001)
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  • 9魏向群,吴春秀,冯昊,李文亮,陈艳欢.腹腔镜与开腹宫颈癌根治术对机体细胞免疫影响的对比研究[J].中国内镜杂志,2016,22(3):1-6. 被引量:29

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