期刊文献+

诺合龙干预治疗高海拔地区糖耐量减低(IGT)临床观察

原文传递
导出
摘要 目的:观察诺合龙对高海拔地区糖耐量减低(IGT)的干预治疗作用。方法:在海拔高于2 000m生活的高危人群健康体检中空腹血糖(FPG)(5.6~7.0)mmol/L及住院和就诊患者中以口服75g葡萄糖耐量试验进行筛查。按1999年WHO符合IGT诊断标准的患者共30例随机分成两组,治疗组予以胰岛素促泌剂诺合龙1mg每天1次;对照组不予以诺合龙及任何降糖药,观察期为1年。两组患者均进行糖尿病教育,强调控制饮食及运动的重要性。结果:治疗组糖尿病的发生率为6.7%;对照组糖尿病发生率为28.6%,两组比较差异有统计学意义(P〈0.05)。结论:诺合龙对IGT干预治疗可明显降低糖尿病的发生率。
作者 冯平
出处 《高原医学杂志》 CAS 2014年第2期38-40,共3页 Journal of High Altitude Medicine
  • 相关文献

参考文献9

  • 1Wild S, Roglic G,Grean A,et al. Global Prevalence of Di-abtes: Estimates for the year 2000 and projections for 2030.Diabetes care,2004,27:1 047 - 1 053.
  • 2潘长玉,朱禧星,李光伟,陆菊明,史虹莉,杨文英.新型口服抗糖尿病药物-瑞格列奈在中国2型糖尿病患者中的疗效及安全性分析[J].中华内分泌代谢杂志,1999,15(6):359-362. 被引量:81
  • 3World Health Organization. Definition, Diagnosis and CLassi-fication ofDiabetes Mellitus and its complications ; Report of aWHO Consultation. Parti : Diagnosis and CLassification ofDiabetes Mellitus. Geneva. World Health Organization,1999.
  • 4McMaster University Evidence Based Practice. Center. Diag-nosis,prognosis and treatment of impaired glucose toleranceand impaired fasting glucose. Evidence Report, 128.
  • 5DECODE Study Group. Age and sex - specific prevalences ofdiabtes and impaired glucose regulation in 13 European Co-horts. Diabetes care,2003,26:61 ?69.
  • 6Gromada J, Dissing S, Kofod II, et al. Effecls of the hypogly-cem ic drugs repaglinide and glibenclamxde on ATP - secsili-re polasssium channels and cyslosolic calcium level in b TC3cells and ral pancrealic b cells. Diabelologia, 1995 , 30:1025.
  • 7Fuhlendorff J, Porsman P,kofod II,et al. Slim ulaiion of in-sulin release by repaglinide and glibenciamide involves bothcommon and dislicl processes. Diabelologia, 1998,47:345.
  • 8陈莉明,王家驰,于德民,张喆,孙丽荣,张宏,谢云,刘春燕,单春艳,郑少雄.诺和龙治疗2型糖尿病189例临床观察[J].中国糖尿病杂志,2002,10(1):62-62. 被引量:33
  • 9Owens D R. Repaglinide 一 prandial glucose regulator, anew class of oral antidiabetic drugs. Diabet Med, 1998,15(suppl4) ;28 -36.

二级参考文献1

  • 1R. Landgraf,H. J. G. Bilo,P. G. Müller. A comparison of repaglinide and glibenclamide in the treatment of type 2 diabetic patients previously treated with sulphonylureas[J] 1999,European Journal of Clinical Pharmacology(3):165~171

共引文献110

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部