D-松醇的研究与开发

The research and development of D-pinitol

D-松醇(D-pinitol,DP)是D-手性肌醇(D-chiro-inositol,DCI)的一种甲基化衍生物,在自然界中具有广泛的植物来源。近年来研究发现,D-松醇具有多种生理活性,如胰岛素增敏作用、降血糖、抗肿瘤、免疫调节、抗炎抗水肿等,因此D-松醇可以应用于医药、保健品原料和膳食补充剂。除此之外,D-松醇作为植物源杀菌剂在农业生产方面的应用也被逐渐推广。广阔的应用范围使D-松醇具备了良好的开发前景。目前对于D-松醇的制备,主要采用化学合成和从天然资源中提取这两种方法,并以后者为主。主要对D-松醇的结构、理化性质、制备、生理活性及D-松醇的应用与开发做简要概述。

D-pinitol is a kind of methylated ramifications of D-chiro-inositol,and there are a wide range of plant sources in nature. In recent years,many research reports suggest that D-pinitol is an active substance with physiological activities including insulin sensitization,hypoglycemia,antitumor,immune regulation,antiinflammatory,etc. Therefore,D-pinitol can be applied to medicine,health food raw materials and dietary supplements. In addition,the application of D-pinitol as a source of plant fungicide in agricultural production has been gradually promoted. And the broad applications of D-pinitolleads to a good development prospect. At present,the preparation methods of D-pinitolwas either from natural plants or chemical synthesis,the former method is more commonly used. In this paper,the research of D-pintol＇s functions,the preparation methods,the applications and development are briefly summarizd.