Mohs显微外科技术在鼻部基底细胞癌治疗中的应用

Application of Mohs microsurgery to treatment of nasal basal cell carcinoma

目的探讨Mohs显微外科技术在鼻部基底细胞癌(BCC)的治疗效果。方法总结广东汕头市潮阳区大峰医院27例采用Mohs显微外科手术治疗的BCC患者的临床资料及治疗结果。结果 27例患者1次手术切除干净20例,2次及2次以上7例;切除后缺损面积从0.5 cm×1.0 cm^2.8 cm×3.5 cm,成形修复术(皮瓣成形和植皮)5例;切口Ⅰ期愈合25例,Ⅱ期瘢痕愈合2例。27例中,失访6例。存活1.5~20年。1例于术后第2年复发,无1例死于基底细胞癌。结论鼻部基底细胞癌采用Mohs显微外科技术具有损伤小、复发率低、安全性好和美容效果好的优点。

【Objective】 To investigate the effect of Mohs microsurgery on nasal basal cell carcinoma（BCC）.【Methods】The clinical data of 27 patients with BCC treated by Mohs microsurgery were summarized.【Results】In the 27 cases, the lesions were resected in 1 surgery in 20 cases, and in 2 and more surgeries in 7 cases with flap defect area from 0.5 cm×1.0 cm to 2.8 cm×3.5 cm, plastic repair（skin shape and skin grafting） in 5 cases. The incision healed by first intention in 25 cases, by stage II scar healing in 2 cases. In the follow-up of the 27 cases, 6cases were lost. The survival time was 1.5 to 20 years. One case had recurrence in the second year after surgery. No one died of basal cell carcinoma. 【Conclusions】Mohs microsurgery is an ideal choice for excising the nasal basal cell carcinoma（BCC）, with minimal wound, low relapse rate, safe and cosmetic results.