摘要
脑出血是一种发病率、致残率及病死率极高的神经系统疾病。脑出血后脑水肿是导致患者病情加重的重要原因，严重影响患者的预后。脑出血后脑水肿形成的机制十分复杂。研究发现，血肿占位效应、凝血酶、血浆蛋白、血红蛋白、细胞因子、基质金属蛋白酶（MMPs）及水通道蛋白-4（AQP4）的表达等在脑出血后周围组织水肿形成过程中都起重要作用。
Intracerebral hemorrhage is a neurological disease with high incidence, morbidity and mortality. Perihematoma edema following intracerebral hemorrhage is the important cause leading to the patient illness, which affects the prognosis of patients seriously. Its formation mechanism is very complicated. The study shows that placeholder hematoma, thrombin, plasma protein, cytokine, Matrix metalloproteinases and aquaporin -4 might play important roles in perihematoma edema formation after intracerebral hemor- rhage.
出处
《国际老年医学杂志》
2015年第2期81-85,共5页
International Journal of Geriatrics
关键词
脑出血
血肿周围水肿
形成机制
Perihematoma edema
Intracerebral hemorrhage
Formation mechanism
