连续性血液净化在危重病合并高钠血症治疗中的应用

Continuous Blood Purification Combined Application of Hypernatremia in the Treatment of Critical Illness

目的对连续性血液净化在危重病合并高钠血症治疗中的应用效果进行探讨。方法随机抽取2012年12月-2013年12月治疗的25例危重病合并高钠血症患者,分析对患者连续性血液净化治疗前后的渗透压、血钠浓度、生理学、病情转归、血钠变化以及APACHEⅡ变化进行对比与分析。结果 25例危重病合并高钠血症患者在接受治疗后,13例死亡,12例存活,存活率为48%。治疗前患者的血钠水平、高血钠持续时间以及APACHEⅡ评分分别是(167.3±7.7)mmol/L,(21.5±2.9)h、(24.4±3.1)分。患者治疗前后的血浆渗透压、血钠浓度、置换液钠浓度等,存在明显差异,具备统计学意义(P<0.05)。结论连续性血液净化在危重病合并高钠血症治疗中的应用,不仅存在明显的治疗效果,而且安全可靠。因此危重病合并高钠血症患者应在早期使用连续性血液净化进行治疗,以改善患者预后。

Objective To merge the application effect of continuous blood purification on hypernatremia in critically ill patients is discussed in. Methods Randomly selected from our hospital in 2012 December - 2013 December treated25 cases of critically ill patients with hypernatremia,purification of the patients with continuous blood osmotic pressure before and after the treatment,the physiological blood sodium concentration,learn,prognosis,changes in serum sodium and APACHE II changes are compared and analyzed through retrospective analysis. Results 25 cases complicated with hypernatremia in critically ill patients receiving treatment in our hospital,13 cases died,12 cases survived,the survival rate was 48%. Before treatment the serum sodium level,high blood sodium duration and APACHE II score were（ 167. 3± 7. 7） mmol / L,（ 21. 5 ± 2. 9） h,（ 24. 4 ± 3. 1） points. Patients before and after treatment of plasma osmotic pressure,serum sodium concentration,replacement of liquid sodium concentration,there are some obvious differences,with statistical significance（ P〈0. 05）. Conclusions Continuous blood purification combined application of hypernatremia in the treatment of critically ill patients,not only has obvious curative effect,safe and reliable. Therefore,critically ill patients with hypernatremia patients should be early in the use of continuous blood purification treatment,to improve the prognosis of the patients.