急性脑梗死后认知功能障碍的相关危险因素分析

Analysis of the risk factors of cognitive impairment after ischemic stroke

目的观察急性脑梗死后认知功能障碍的危险因素,为早期预防和早期治疗提供依据。方法急性脑梗死290例患者,应用MMSE筛查出入院3d内发生认知功能障碍者,观察急性脑梗死后认知功能障碍的发生率,并对影响其发生的危险因素进行分析。结果急性脑梗死后认知功能障碍的发生率22.9%;年龄、糖尿病史、卒中或TIA史、多发性脑梗死、梗死面积大、左半球梗死为急性脑梗死后认知功能障碍发生的危险因素。结论急性脑梗死后认知功能障碍发生率较高;年龄、卒中或TIA史、糖尿病史、多发性脑梗死体积、梗死面积大、左半球梗死为急性脑梗死后认知功能障碍发生的危险因素。

Objective To analyze the risk factors of cognitive impairment after ischemic stroke and provide evidence for early diagnosis and therapy.Methods Totally 290 patients with ischemic stroke were undergone mini mental state examination（MMSE）to screen out cognitive impairment within 3days of hospitalization.We observed the incidence of cognitive impairment and analyze the related risk factors.Results The incidence of cognitive impairment after ischemic stroke was 22.9%.The main risk factors included age,history of diabetes,stroke,transient ischemic attack,multi-infarct,large-infarct and leftbrain infarct.Conclusion The incidence of cognitive impairment after ischemic stroke is high.The age,history of diabetes,stroke,transient ischemic attack,multi-infarct,large-infarct and left-brain infarct are the risks factors of cognitive impairment after ischemic stroke.