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希罗达为基药的同步放化疗用于胃癌根治后疗效观察

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摘要 目的:探讨希罗达为基药的同步放化疗用于胃癌根治后的临床治疗效果。方法:选取来我院进行治疗的胃癌患者148例,按照治疗方式的不同分为对照组和观察组,每组患者74例。对照组患者单纯使用放化疗进行治疗,观察组患者在对照组治疗的基础上加用希罗达药物进行治疗,对患者进行为期一年的随访,观察两组患者的生存率情况,比较两组患者不良反应情况发生的几率。结果:经过治疗后,观察组患者的生存率明显高于对照组患者,P<0.05,具有显著性差异和统计学意义。在不良反应发生情况方面,对照组患者发生的几率明显高于观察组患者,P<0.05,具有显著性差异和统计学意义。结论:希罗达应用于放化疗治疗胃癌根治后的临床中效果较为显著,能够降低毒性反应,提高患者的耐受性,具有极强的临床应用价值。 Objective:To investigate the Shiroda based medicine synchronous radiotherapy and chemotherapy for gastric cancer after the clinical treatment effect.Methods:gastric cancer treatment cases,in accordance with the different treatments for the control group and the observation group,74 cases in each group of patients. Control group patients were treated with radiotherapy and chemotherapy treatment,the patients in observation group were treated with Xeloda plus drugs based on the treatment in control group,to carry out a one-year follow-up of patient,to observe the survival condition of two groups of patients were compared between the two groups,the probability of adverse reactions occur. Results: after treatment,observe the survival rate was significantly higher than the patients in the control group.Cases occurred in the adverse reaction,the control group was significantly higher than the probability of occurring in patients in the observation group,P〈0.05,with significant differences and statistical significance. Conclusion:the clinical effect of radiotherapy and chemotherapy of Xeloda is applied to the treatment of gastric cancer after the more obvious,can reduce the toxicity,enhance the tolerance of patients,with strong clinical value.
出处 《药物与人》 2015年第2期19-19,共1页 Medicine & People
关键词 希罗达 同步放化疗 胃癌根治 Shiroda;concurrent chemotherapy;gastric cancer
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  • 1王敏桦,孙菁,曾昭冲,杜世锁,曾蒙苏,孙益红.胃癌术后复发转移类型及其对放疗靶区设计的临床意义[J].实用肿瘤杂志,2007,22(3):218-220. 被引量:13
  • 2Hermans J,Bonenkamp JJ,Boon MC,et al.Adjuvant therapy after curative resection for gastric cancer:meta-analysis of randomized trials [J].J Clin Oncol,1993,11(8):1441-1447..
  • 3Earle CC,Maroun JA.Adjuvant chemotherapy after curative resection for gastric cancer in non-Asian patients:revisiting a meta-analysis of randomised trials [J].Eur J Cancer,1999,35(7):1059-1064..
  • 4Macdonald JS,Smalley SR,Benedetti J,et al.Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction [J].N Engl J Med,2001,345(10):725-730.
  • 5Kim S,Lim DH,Lee J,et al.An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach [J].Int J Radiat Oncol Biol Phys,2005,63(5):1279-1285.
  • 6International Commission on Radiation Units and Measurements (ICRU).Report Number 50.Prescribing,recording and reporting photon beam therapy[C].Washington:D.C.ICRU,1993..
  • 7Trotti A,Colevas AD,Setser A,et al.CTCAE v3.0:development of a comprehensive grading system for the adverse effects of cancer treatment [J].Semin Radiat Oncol,2003,13(3):176-181.
  • 8Park SH,Kim DY,Heo JS,et al.Postoperative chemoradiotherapy for gastric cancer [J].Ann Oncol,2003,14(9):1373-1377.
  • 9Hughes BG,Yip D,Chao M,et al.Audit of postoperative chemoradiotherapy as adjuvant therapy for resected gastroesophageal adenocarcinoma:an Australian multicentre experience [J].ANZ J Surg,2004,74(11):951-956.
  • 10Leong CN,Chung HT,Lee KM,et al.Outcomes of adjuvant chemoradiotherapy after a radical gastrectomy and a D2 node dissection for gastric adenocarcinoma [J].Cancer J,2008,14(4):269-275.

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