住院精神分裂症患者口腔健康相关生活质量影响因素及其与自杀企图的关系

Related Factors of Oral Health Related Quality of Life in Chinese Schizophrenia Inpatients and Its Relationship with Suicide Attempt

目的:分析住院精神分裂症患者口腔健康相关生活质量的影响因素和自杀企图发生率,并探索口腔健康相关生活质量与自杀企图的关系。方法:2013年5月7-27日,将来自首都医科大学附属北京安定医院94例住院精神分裂症患者连续入组,分为自杀企图组(7例)和非自杀企图组(87例),采用自制调查表、口腔健康影响程度量表(OHIP-14)、简明精神病评定量表(BPRS)和日常生活功能量表(ADL)对其进行横断面调查;并运用多因素线性回归方法(逐步法),对住院精神分裂症患者口腔健康相关生活质量的相关因素进行回归分析。结果:住院精神分裂症患者OHIP-14总分为(10.9±11.8)分,自杀企图发生率为8.0%;自杀企图组在OHIP-14总分、功能受限、疼痛与不适、心理社会影响和独立能力减弱评分均高于非自杀企图组(F=9.138,6.193,8.285,10.355,6.628;P<0.05),差异有统计学意义;其BPRS评分和ADL评分均高于非自杀企图组(F=3.143,0.649;P>0.05),差异无统计学意义;口腔健康相关生活质量的4个领域中,功能受限得分、疼痛与不适得分、心理社会影响得分和独立能力减弱得分之间的相关系数均呈正相关;病程、有无自杀企图、月收入状况和受教育程度等评分与住院精神分裂症患者口腔健康相关生活质量评分相关(P<0.05)。结论:住院精神分裂症患者口腔健康相关生活质量与多种因素存在相关,包括病程、是否有自杀企图、月收入和受教育程度等,这为制定改善住院精神分裂症患者口腔健康相关生活质量的综合干预方案提供了参考依据。

Objective：To investigate the impact of oral health related quality of life（OHRQOL）in Chi-nese schizophrenia inpatients and their incidence of suicide attempts,and explore the relationship between OHRQOL and suicide attempts.Methods：A total of 94 schizophrenia inpatients were consecutively exam-ined in Beijing An＇ding Hospital,Capital Medical University,in China from May 7,2013 to May 272,013 . And all subjects included suicide attempters（n=7）and non-attempters（n =87）were investigated with self-made questionnaire,oral health impact profile（OHIP-14）,brief psychiatric reacting scale（BPRS） and activity of daily living scale（ ADL） .Multi-factor linear regression method（ method step by step） was used to assess associated variables and OHRQOL in Chinese schizophrenia inpatients.Re sutls ：OHIP-14 total score was （10.9 ±11.8）,and the prevalence of suicide attempt was 8.0%.Compared to the non-attempters,the attempters had higher points in OHIP-14 total score,the score of functional limitation,the score of pain and discomfort,the score of psychological discomfort,and the score of independent ability（ P0.05）.In four fields of OHRQOL,the score of functional limitation,the score of pain and dis-comfort,the score of psychological discomfort,and the score of independent ability were positively correla-ted between each other.Multi-factor linear regression analysis showed that course of disease,the pres-ence of suicide attempts,monthly income status,and level of education were associated with OHRQOL in Chinese schizophrenia inpatients（ P〈0.05 ） .Conclusion：OHRQOL of schizophrenia inpatients may be related with many factors,including course of disease,the presence of suicide attempts,monthly income status,and level of education.It will provide referential basis for the comprehensive intervention plan that was in order to improve OHRQOL of schizophrenia inpatients.