中医药治疗肺纤维化研究进展

Research Progress of Traditional Chinese Medicine Treatment in Treating Pulmonary Fibrosis

目前,中医药治疗肺纤维化在理论和临床方面取得了较好成果,但仍存在着一些问题,如多以西医建立的肺纤维化疾病模型为研究对象,不能体现中医证型特色,很难把握证候的演变规律。西医治疗主要是糖皮质激素、免疫抑制及细胞毒药物的联用或单用,但至今仍不能表明何种疗法能提高肺纤维化患者生存率、改善生存质量,而中医药可改善肺纤维化患者的症状,延缓肺功能的减退,提高患者的生存质量,且安全可靠。尤其与小剂量激素合用,比单用激素疗效好,又能减轻激素的不良反应,起到协同增效的作用。

At present,Chinese medicine treatment for pulmonary fibrosis has achieved good results in theory and clinic,but there are still some problems,such as much model of pulmonary fibrosis disease in western medicine can＇ t embody TCM syndrome characteristics,it is difficult to grasp the evolution rule of syndrome. Western medicine mainly glucocorticoids,immunosuppression,and in the administration of cytotoxic drugs or alone,but still can＇t show which therapy can improve the survival rate and life quality. Traditional Chinese medicine can improve the symptom of the patients with pulmonary fibrosis,delay the decline of lung function and improve the patient＇s survival quality,safe and reliable. Especially with small dose of hormone combination can reduce the side effect of hormone and achieve the effect of synergies.