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42例脑梗死患者血清同型半胱氨酸水平研究 被引量:8

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摘要 目的:观察脑梗死患者血清Hcy水平变化,探讨血清Hcy水平与脑梗死的关系,为脑梗死的临床治疗提供新思路。方法:随机选取2013-05~2014-05在佳木斯大学附属第一医院神经内科脑梗死患者42例作为病例组,按照对照组与病例组性别相同,年龄相差5岁以内,随机选择同期在该科室就诊的非脑梗死患者42例作为对照组。入院后分别检测两组患者血清Hcy、血清TC、血清TG、血清HDL-C、血清LDL-C。比较两组患者血清TC、血清TG、血清HDL-C、血清LDL-C及血清Hcy浓度有无差异,同时分析血浆血清Hcy水平与血清TC、血清TG、血清HDL-C、血清LDL-C的相关性。结果:病例组患者血清Hcy、血清TC和血清TG均高于对照组(P〈0.05),而血清HDL-C和血清LDL-C与对照组比较无差异(P〉0.05);病例组患者血清Hcy与血清TC、血清TG存在正相关关系(P〈0.05),其相关系数r分别为0.3112和0.4914;血清Hcy与血清HDL-C、血清LDL-C不存在相关性(P〉0.05);对照组患者血清Hcy与血清TC、血清TG、血清HDL-C、血清LDL-C均不存在相关性(P〉0.05)。结论:血清Hcy水平升高和高脂血症(血清TC和血清TG水平升高)是脑梗死的危险因素,有效控制血清Hcy水平,合理降脂,可有效降低脑梗死的发生率。
出处 《黑龙江医药科学》 2015年第1期86-87,共2页 Heilongjiang Medicine and Pharmacy
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