中医药治疗慢性乙型肝炎肝纤维化用药规律

Medication Law in Treating Liver Fibrosis due to Chronic Hepatitis B by Chinese Medicine

目的:探讨中药治疗慢性乙肝肝纤维化的用药规律。方法:收集2004年6月至2014年6月中医治疗慢性乙型肝炎肝纤维化的文献,进行统计分析。结果:共收集77篇文献,涉及中药153味,累计870味次;使用频率2.0%以上的中药共15味,累积频率57.95%;最常用的5类药是:补虚药、活血化瘀药、清热药、利湿药、解表药,累积频率84.92%。结论:目前临床治疗慢性乙型肝炎肝纤维化是以扶正补虚和活血化瘀为主,辅以清热、除湿、行气、化痰、软坚散结等。

Objective：To explore medication laws in treating liver fibrosis due to chronic hepatitis B by Chinese medicine.Methods：To collect the literatures（from June 2004 to June 2014） on treating liver fibrosis due to chronic hepatitis B by Chinese medicine,and to analyze them statistically.Results：A total of 77 literatures were collected,involved 153 herbs which were used cumulatively 870 times;there was a total of 15 herbs whose using frequencies were above 2.0%,cumulative frequency was 57.95%;5 kinds of the most commonly used drugs are：invigorating for deficiency,promoting blood circulation for removing blood stasis,clearing away heat,removing dampness,relieving the exterior syndrome,whose cumulative frequency was 84.92%.Conclusion：At present,the clinical treatment of liver fibrosis due to chronic hepatitis B is mainly based on tonifying vital Qi and invigorating deficiency,promoting blood circulation for removing blood stasis,and combined with clearing away heat,removing dampness,promoting Qi circulation,resolving phlegm,resolving hard lump etc.