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茶多酚对维持性血液透析患者心脏功能的影响 被引量:3

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摘要 目的研究口服茶多酚对维持性血透患者心脏功能的影响,并探讨其可能机制。方法老年患者60例维持性血液透析患者随机分为茶多酚组及常规组,比较两组心脏超声指标左室舒张末期内径(LVDd)、左室舒张末期内径(LVDs)左房内径(LAD)、室间隔厚度(IVST)、左室后壁厚度(PWT);炎症指标:IL-6、TNF-α及NF-κB;体内铁状态:铁蛋白(SF)及转铁蛋白饱和度(TSAT)。结果口服茶多酚3个月后茶多酚组与对照组相比,LVDd、LVDs、PWT明显下降,P<0.05;IL-6、TNF-α及NF-κB显著表达减少,P<0.05;SF及TSAT显著下降,P<0.05。结论口服茶多酚可能通过改善体内铁过载及减轻体内微炎症状态,从而改善了患者的心脏功能。
出处 《海峡药学》 2015年第2期105-107,共3页 Strait Pharmaceutical Journal
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