立方氧化亚铜的制备及在无酶葡萄糖传感器中的应用

Preparation of Cu_2O and its application in nonenzymatic glucose sensor

通过液相法合成了立方氧化亚铜，利用 Nafion 将氧化亚铜固定在玻碳电极（GCE）表面，制备了 Nafion / Cu2 O/ GCE 电极用于构建无酶葡萄糖传感器.采用 XRD 和 SEM 对氧化亚铜的结构和形貌进行了表征，利用循环伏安法（CV）和计时电流法（CA）研究了该修饰电极对葡萄糖的电催化活性.结果表明，在0.1 mol/ L NaOH 溶液为支持电解质的体系中，Nafion / Cu2 O/GCE 电极对葡萄糖有明显的电催化响应，且该传感器在葡萄糖浓度为7.5×10-5~2.0×10-2 mol/ L 范围内具有良好的线性关系，相关系数 R 为0.9994，具有低的检出限0.375×10-6 mol/ L （S / N =3），高的灵敏度315.6μA mM -1 cm -2.

Cuprous oxide（Cu2 O）was synthesized by liquid phase method and fixed on glassy carbon elec-trode surface by Nafion,preparing Nafion / Cu2 O/ GCE modified electrode to fabricate a nonenzymatic glucose sensor. The morphology and structure of Cu2 O were characterized by SEM and XRD. The electrochemical performance of the modified electrode was investigated using cyclic voltammetry（CV）and chronoamperome-try（CA）. It showed that electrocatalytic activity of Nafion / Cu2 O/ GCE modified electrode towards glucose was better than bare glassy carbon electrode in 0. 1 mol/ L NaOH solution. The sensor showed a good linear relationship for glucose concentration over the range of 7. 5 × 10 - 5 ~ 2. 0 × 10 - 2 mol/ L（R = 0. 999 4）with low detection limit of 0. 375 × 10 - 6 mol/ L（S / N = 3）and high sensitivity of 315. 6 μA mM - 1 cm - 2 .