本院2011-2013年儿科门诊手足口病处方评价分析

The Evalution and Analysis of Hand-Foot-Mouth Disease Prescription in the Outpatient of Our Hospital from 2011 to 2013

目的:了解本院儿科门诊手足口病的发病情况及用药特点,为预防、治疗、控制手足口病提供科学依据。方法:随机抽取本院2011年1月-2013年12月儿科门诊处方24 000张(8000张/年,2000张/季度),对确诊为手足口病的处方进行评价分析。结果:2011-2013年本院儿科门诊手足口病例数占儿科门诊总病例数的比例分别为:2.95%、3.21%、3.70%,6岁及其以下的儿童发病人数为744例,占处方总数的94.30%,3岁及其以下患儿发病比例为66.20%,发病高峰期为4-6月份;本院儿科门诊治疗手足口病主要以抗病毒治疗为主,继发细菌感染时在临床药师的指导和干预下合理使用抗菌药物,根据患儿病情合理联合使用维生素、免疫增强剂、糖皮质激素等药物。结论:本院儿科门诊手足口病发病率呈逐年上升趋势,发病有明显的季节性特点,本院儿科门诊治疗手足口病以抗病毒治疗为主,在临床药师的指导干预下,合理规范化使用抗菌药物,保证了儿童用药安全。

Objective： To understand the incidence and feature in choosing drugs of hand-foot-mouth disease in the outpatient of our hospital,in order to provide a scientific basis for prevention care and control for hand-foot-mouth disease. Method：24 000 prescriptions（8000 prescriptions/year,2000 prescriptions/quarter） of pediatric outpatient were taken randomly from January 2011 to December 2013 in our hospital, the part of them were hand-foot-mouth diseases prescription, which should be evaluated.Result： From 2011 to 2013, the number of cases in proportion to the total number cases of the outpatient in our hospital were respectively 2.95%,3.21%,and 3.70%.The number of child mortality under the age of 6 were 744 cases, which accounted for 94.30% of the total prescriptions, and children under the age of 3 accounted for 66.20%, and the morbidity peak was from May to July.In our hospital, we mostly based on antiviral treatment to treat hand-foot-mouth disease in the outpatient.Under the guidance and intervention of clinical pharmacists when secondary bacterial infection. According to the illness of children, we used reasonable combination of vitamins, immune enhancer, corticosteroids and other drugs. Conclusion： There is an upward trend in incidence of hand-footmouth diseases in the outpatient of our hospital, the disease has obvious seasonal characteristic, our hospital mostly based on antiviral treatment to treat hand-foot-mouth disease in the outpatient.Under the guidance and intervention of clinical pharmacists, we use antimicrobial agents rationally and ensure the drug safety of children.