新生儿重症高胆红素血症临床危险因素分析

Clinical Risk Factors Analysis of Neonatal Intensive High Blood Bilirubin

目的:研究分析新生儿重症高胆红素血症的临床危险因素。方法:选取本院2010年6月-2011年6月新生儿科病房所收治的患儿共520例,将其分为出现重症高胆红素症状的观察组患儿与未出现高胆红素血症的对照组患儿各260例。通过归纳整合两组患儿的具体病因、病理机制、临床症状、治疗效果等数据信息,应用logistic回归模型,对高胆红素血症的常见病因如感染、头颅血肿、窒息、早产等因素进行回顾性分析。结果:观察组与对照组、体重、贫血等方面比较差异均具有统计学意义(P<0.05)。进行回顾性分析后发现,影响新生儿重症高胆红素血症的临床危险因素主要有感染、早产、头颅血肿、窒息、溶血。结论:新生儿重症高胆红素血症的临床危险因素种类繁多,其中主要的危险因素包括感染、早产、头颅血肿、溶血等。及时确定与准确把握这些临床危险因素,能够在一定程度上有效降低新生儿高胆红素血症的发生几率,同时也能够为该病症的临床诊疗活动提供有益的参考与指导。

Objective：To study the clinical risk factors of neonatal intensive high blood bilirubin.Method：A total of 520 cases of neonatal intensive high blood bilirubin were selected from June 2010 to June 2011 in new pediatric ward in our hospital, the children were divided into observation group with severe high bilirubin symptoms and does not appear high bilirubin concentration in the control group with 260 cases each.By induction of integration of the two groups of children with specific etiology,pathological mechanism,clinical symptom,therapeutic effects,such as data and information, using logistic regression model,the common causes of high blood bilirubin in such as infection,cranial hematoma,asphyxia,preterm labor were analyzed retrospectively.Result：The clinical data of observation group and control group,both the risk for age,body weight,jaundice,congenital disease,hepatitis, anemia,etc,were significant difference（P0.05）.Using logistic regression model were retrospectively analyzed and found that affects newborn children severe high blood bilirubin clinical risk factors mainly include infection,premature birth,cranial hematoma,hemolysis and other factors.Conclusion：Neonatal intensive high bilirubin levels,there are many different kinds of clinical risk factors,the main risk factors include infection,premature birth,cranial hematoma,hemolysis,etc.Determining timely and accurately grasp the clinical risk factors,to some extent,can effectively reduce the neonatal bilirubin levels,high risk,at the same time can also be for clinical diagnosis and treatment of the disease involve activities provide the beneficial reference and guidance.