MP感染与小儿支气管哮喘的关系及对患儿免疫指标的影响

The relationship between Mycoplasma pneumoniae infection and pediatric asthma and the effects of the infection on immune parameters in the children

目的探讨肺炎支原体(MP)对支气管哮喘患儿发病的影响。方法收集2011年3月至2014年2月收治的98例支气管哮喘的患儿作为实验组,另选取100例呼吸道感染的患儿为对照组,然后检测两组患儿血清中MP的阳性率、Ig E水平及外周血中嗜酸粒细胞的量。结果实验组患儿的MP的阳性率为明显高于对照组患儿;年龄越大的支气管哮喘患儿的MP的阳性率越高;MP阳性患儿的Ig E水平及嗜酸粒细胞的量均明显高于MP阴性患儿。结论 MP感染是导致小儿支气管哮喘发病的一种危险因素。

Objective To explore the effect of Mycoplasma pneumoniae（ MP）infection to the incidence of pediatric asthma. Methods Ninety-eight patients with asthma who came to our hospital from March 2011 to February 2014 were collected as the experimental group. Another 100 patients with respiratory tract infections were collected as control group. Serum MP positive rate,the level of IgE and the amount of peripheral blood eosinophils of the two groups were detected. Results The MP positive rate of the experimental group was significantly higher than the con-trol group,and it was higher in the older children with asthma. The level of IgE and the amount of peripheral blood eosinophils of the MP-positive children were higher than the MP-negative children. Conclusion MP infection is a risk factor for pediatric asthma.