止血凝胶封闭微创经皮肾通道的安全性及可行性研究

Study of the safety and feasibility of tubeless percutaneous nephrostolithotomy by hemostasis gel closure of mini-percutaneous renal-channel

目的 研究止血凝胶封闭微创经皮肾通道的安全性及可行性.方法 采用MPCNL治疗的简单性肾结石及输尿管上段结石80例,对照组术后放置14 F肾造瘘管,实验组采用止血凝胶封闭微创经皮肾通道,不放置肾造瘘管,手术为单通道.统计学分析对照组与实验组术后患者疼痛需要应用镇痛药物的发病率和剂量、手术后患者血红蛋白下降情况、术后患者术后出现持续出血,感染及尿外渗等并发症发生情况以及手术后住院的时间.结果 两组患者均一期手术成功,对照组患者术后疼痛需要应用镇痛药物的发病率明显高于实验组（42.5％ vs 20％）,而术后出现出血、感染等并发症的发病率以及手术后的住院时间,差异无统计学意义（P＞0.05）.两组患者术后复查均未出现肾周围血肿,对照组患者出现7例拔出造瘘管后的漏尿.结论 止血凝胶封闭微创经皮肾通道的经皮肾碎石取石术降低了患者手术后的痛苦,避免手术后拔出肾造瘘管漏尿的发病率,对于简单的肾结石和输尿管结石患者是安全可靠的手术方式.

Objective To study the safety and feasibility of tubeless percutaneous nephrostolithotomy by hemostasis gel closure of mini-percutaneous renal-channel.Methods Eighty patients after conventional percutaneous nephrostolithotomy are selected and divided into two groups according to the principle of randomization.Control group adopts conventional percutaneous nephrostolithotomy calculi lithotripsy with renal pelvis drainage tube placement whereas the experimental group adopts tubeless percutaneous nephrostolithotomy by hemostasis gel closure of mini-percutaneous renal channel.Both experimental group and control group will be scientifically and statistically analyzed via the incidence and the dose of using sedative for alleviating pain after operation,hospital stay,level of hemoglobin,and the occurrence of complications such as continuate hemorrhage,infection,urinary extravasation,etc.Results The operation of both groups are successful in phrase Ⅰ.The incidence and the dose of using sedative in control group are obviously higher than that in experimental group（45% vs 20%）.However,the incidence of postoperative complications like infection and hemorrhage and hospital stay between two groups are undifferentiated in statistics（P 〉 0.05）.Neither the experimental group nor the control group has perinephric hematoma,and seven cases of control group have urinary leakage after remove of fistula.Conclusion Tubeless percutaneous nephrostolithotomy by hemostasis gel closure of mini-percutaneous renal-channel is safe and feasible and it can reduce the incidence of postoperative pain and avoid urinary leakage.