重型颅脑损伤术后早期肠内营养支持的疗效

The curative effect of early enteral nutrition on treating patients with postoperative severe brain injury

目的分析重型颅脑损伤术后早期肠内营养支持治疗的临床价值。方法选择在本院接受手术治疗的重型颅脑损伤患者92例作为研究对象,随机分为术后肠外营养的对照组患者及术后早期肠内营养的观察组患者,比较其置管前后营养指标及免疫功能指标等差异。结果观察组总蛋白(58.23±3.68)g/L、前白蛋白(248.17±34.32)mg/L及血红蛋白含量(129.36±19.54)g/L、细胞免疫CD8、CD4/CD8(36.76±4.32、25.14±4.34、1.85±0.36)、体液免疫指IgG、IgA、IgM(14.33±3.12、2.47±0.41、1.17±0.34)g/L均明显高于对照组。结论重型颅脑损伤术后早期肠内营养支持治疗有助于改善患者的营养水平,且利于提高患者的整体免疫功能,具有积极的临床意义。

Objective To investigate the curative effect of early enteral nutrition on treating patients with postoperative severe brain injury. Methods Totally 92 patients with postoperative severe brain injury were randomly divided into control group （treated with postoperative parenteral nutrition） and observation group （treated with early postoperative enteral nutrition, nutrition）. The nutritive index and immune function of two groups before and after catheter was compared. Results The total protein（58. 23±3.68） g/L, prealbumin （248.17±34.32） mg/L, hemoglobin content （129. 36±19.54） g/L, CD8, CD4,CD4 / CD8 （36.76±4.32, 25.14±4.34, 1.85±0.36）, IgG, IgA and IgM （14.33±3.12） g/L, （2.47±0.41） g/L and （1.17±0. 34） g/L in the observation group were higher than these in the control group. Conclusion Early postoperative severe brain injury enteral nutrition therapy can effectively improve patients; nutritional condition and immune function, which is worthy of application.