青春痘的病原学研究

Etiology study of acne

目的:探讨青春痘的细菌感染状况,对分离菌株进行药敏试验,为青春痘的防治提供病原学诊断依据和抗菌药物治疗指导方案.方法:随机收集青春痘患者58例,采集患处标本按照常规纯化菌株进行细菌鉴定,并用纸片扩散法进行药敏试验,筛选对细菌敏感的药物.结果:58份样本中鉴定分离出有意义的细菌,表皮葡萄球菌对抗菌素SAM、AMC、VA和KZ敏感,金黄色葡萄球菌对SAM、AMC、VA、KZ、FOX和RD敏感;泉居沙雷氏菌、粘质沙雷氏菌和土生克雷伯菌对常用抗菌药物敏感.结论:青春痘细菌感染最为多见的病原菌是表皮葡萄球菌和金黄色葡萄球菌.对于青春痘的防治应该综合多种因素,适当应用抗菌药物是治疗和控制病情的重要手段.

AIM： To investigate the bacterial pathogenesis of ac- ne, and to perform drug sensitive test for separated the bacteria species. To provide etiology diagnosis basis and guidelines of anti- biotics treatment. METHODS： Fifty eight patients with acne were collected randomly, skin specimens were collected according to the conventional purification identification of bacteria strains, and drug sensitive test was performed by disk diffusion method, screening drug sensitive bacteria. RESULTS： Useful bacteria were separated and identified in those 58 samples. Staphylococcus epidermidis was sensitive to antibiotics SAM, AMC, VA and KZ. Staphylococcus anreus was sensitive to SAM, AMC, VA, KZ, FO and RD. Serratia fonticola, Serratia marcescens, Klebsiella terri- gena were sensitive to commonly-used antimicrobial drug sensitivi- ty. CONCLUSION： Staphylococcus epidermidis and Staphylo- coccus aureus are the most common pathogens. Several factors should be considered comprehensively in order to prevent acne. The application of appropriate amount of antibiotics is an impor- tant treatment of acne.