外围含偶氮苯基团的温敏性聚合物包覆的金纳米粒子的合成及性能研究

Synthesis and property of thermosensitive polymer-coated gold nanoparticles with periphery of azobenzene moiety

通过4-二甲氨基吡啶稳定的金纳米粒子(DMAP-AuNPs)与含偶氮苯端基的聚N-异丙基丙烯酰胺(PNIPAM-AZO)进行配体置换,制备了外围舍偶氮苯基团的聚N-异丙基丙烯酰胺包覆的金纳米粒子(PNIPAM-AuNPs),并通过紫外-可见吸收光谱、透射微镜、红外光谱和核磁共振氢谱对其结构和形貌进行了表征。温敏性研究结果表明,PNIPAM-AuNPs具有低临界溶解温度(LCST),通过透过率和粒径随温度变化测得其LCST分别为36℃和35.5℃。在PNIPAM-AuNPs发生相转变前后,金纳米粒子的表面等离子共振(SPR)吸收特征峰由517.6nm红移至590nm。

Poly（N-isopropylacrylamide）-coated gold nanoparticies（PNIPAM-AuNPs） with periphery of azobenzene moiety were synthesized by ligand exchange between azobenzene-terminated poly （N-isopropylacrylamide）（PNIPAM- AZOC） and 4-dimethylaminopyridine stabilized gold nanoparticles（DMAP-AuNPs）, and the structure and morphology of the as-synthesized AuNPs were characterized by UV-Vis, TEM, FT-IR and： H-NMR. The results showed that PNIPAM-AuNPs had a lower critical solution temperature（LCST） with 36℃ and 35.5℃ determined through the change of transmittance and particle diameter with the change of temperature respectively. The characteristic peak of the surface plasmon resonance（SPR） absorption of the PNIPAM-AuNPs redshift to 590 nm from 517.6 nm after the phase transition.