不同病因的慢性咳嗽89例临床特征分析

To Explore the Characteristics of Chronic Cough Between Different Etiology Based on 89 Cases

目的提高对慢性咳嗽的认识及诊断水平。方法收集就诊的慢性咳嗽患者,按照中国咳嗽诊治指南推荐的诊断流程及各种常见慢性咳嗽诊断标准,予以胸部影像学、肺功能+支气管激发试验(拒绝激发试验者,予以峰流速测试)、诱导痰检测等,确定慢性咳嗽病因。然后给予针对性治疗。结果慢性咳嗽常见病因为依次为变应性咳嗽(AC)、上气道咳嗽综合征(UACS)、咳嗽变异哮喘(CVA)、嗜酸粒细胞性支气管炎(EB)、胃食管反流性咳嗽(GERC)。各不同组间在患病人群、临床表现、化验检查方面有所不同。结论慢性咳嗽是临床常见病,病因不同,引起咳嗽发病机制不同,临床应采取不同治疗方法。

Objective To improve the recognition and diagnosis level of chronic cough. Methods The clinic patients with chronic cough were selected. According to the Chinese guidelines recommended diagnostic process of coughing and all kinds of common criteria, the tests including chest imaging, lung function ＋ bronchial provocation tests（refused to motivate participants to peak velocity testing）, induced sputum examination were adopted for the patients to determine the cause of chronic cough. And then the patients were given specific therapy. Results The common causes of chronic cough were allergic cough, upper airway cough syndrome（UACS）, cough variant asthma（CVA）, acidophilic granulocyte bronchitis（EB）, gastroesophageal reflux cough（GERC）. Between the different groups, the population, clinical manifestation and laboratory examination were different. Conclusion Chronic cough is a clinical common disease. We should use different treatments based on the different cause and pathogenesis.