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专题综述:动脉粥样硬化易损斑块与缺血性卒中 被引量:1

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摘要 多年来的研究已经表明,源于冠状动脉研究的易损斑块概念适用于脑血管床,尤其是颅外段脑动脉。大多数颅外段或颅内段大动脉粥样硬化导致的缺血性卒中和短暂性脑缺血发作病例是由易损/不稳定动脉粥样硬化斑块破裂基础上血栓栓塞所致的。易损斑块的病理形态特征为影像学评估提供了多个潜在的目标。因此,对于症状性和无症状性颅内外脑动脉粥样硬化患者,利用血管壁和斑块成像技术识别潜在的脑血管易损斑块将有助于预测患者的卒中风险和指导治疗选择,同时还有助于研充脑动脉粥样硬化的自然史,提高缺血性卒中的一级和二级预防的水平。目前,冠状动脉和颅外段颈动脉易损斑块的影像学检测在临床上的应用日益增多,但是颅内动脉易损斑块成像尚处在起步阶段。
作者 曹亦宾
出处 《中国卒中杂志》 2015年第3期242-247,共6页 Chinese Journal of Stroke
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