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盐酸帕洛诺司琼预防下腹部手术后恶心呕吐30例临床观察

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摘要 目的:观察盐酸帕洛诺司琼预防下腹部手术后患者恶心呕吐的临床疗效。方法:选择60例行择期下腹部手术并在术后接受静脉镇痛的患者,随机分为观察组与对照组各30例。观察组给予盐酸帕洛诺司琼治疗,对照组给予托烷司琼治疗。观察并记录两组手术结束后1d和2d内的恶心、呕吐程度,计算两组患者恶心、呕吐的控制率,记录患者头痛、腹胀等不良反应的发生情况,并对两组患者进行视觉模拟评分(VSA)。结果:两组患者术后1d经药物预防治疗后的恶心及呕吐有效控制率间差异统计无统计学意义(P>0.05);观察组在术后两天的恶心和呕吐有效控制率显著优于对照组(P<0.05)。两组患者在术后的不良反应发生情况及VSA评分差异无统计学意义(P>0.05)。结论:盐酸帕洛诺司琼预防下腹部手术后恶心呕吐疗效较好,值得临床推广。
出处 《中国民族民间医药》 2015年第6期50-50,52,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
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  • 1葛淑芝,董悦.腹腔镜胆囊切除术的护理1670例[J].中国实用护理杂志,2004,20(10):26-27. 被引量:77
  • 2袁荷梅,丁乾杰.昂丹司琼预防腹腔镜手术患者PONV的疗效观察[J].山东医药,2006,46(10):27-27. 被引量:3
  • 3陈映霞,秦叔逵,程颖,陈振东,李进,张清媛,潘良熹.盐酸帕洛诺司琼预防化疗性恶心呕吐的多中心双盲随机对照临床研究[J].临床肿瘤学杂志,2007,12(3):161-165. 被引量:48
  • 4Stadler M, Bardiau F, Seidel L, et al. Difference in risk factors or postoperative nausea and vomiting. Anesthesiology, 2003,98 (1):46-52.
  • 5Kovae AL. Prevention and treatment of postoperative nausea and vomiting. Drugs, 2000,59 ( 2 ) : 213-43.
  • 6Eisenberg P, Figueroa-Vadillo J, Zamora R, et al. Improved prevention of moderately emetogenic chemotherapy-induced nausea and vomiting with palonosetron, a pharmacologicallynovel 5-HT3 receptor antagonist-Results of a phase m, single- dose trial versus dolasetron. Cancer, 2003,98 ( 11 ) : 2473-2482.
  • 7Chua DT, Sham JS, Kwong DL, et al. Comparative efficacy of three 5-HT3 antagonists (granisetron, ondansetron, and tropisetron) plus dexamethasone for the prevention of cisplatin- induced acute cmesis: a randomized crossover study. Am J Clin Oncol, 2000,23(2) : 185-191.
  • 8Stoltz R, Parisi S, Shah A, et al. Pharmacokinetics metabolism and excretion of intravenous palonosetron in healthy human volunteers. Biopharm Drug Dispos, 2004,25 (8) : 329-337.
  • 9Massa E, Astara G, Madeddu C, et al. Palonosetron plus dexamethasone effectively prevents acute and delayed chemothe- rapy induced nausea and vomiting following highly or moderately emetogenic chemotherapy in pretreated patients who have failed to respond to a previous antiemetic treatment: comparison between elderly and non-elderly patient response. Crit Rev Oncol Hematol, 2009,70( 1 ) : 83-91.
  • 10Sepulveda-vildosola AC, Betanzos-cabrera Y, Lastiri GG, et al. Palonosetron hydrochtoride is an effective and safe option to prevent chemotherapy-induced nausea and vomiting in children. Arch Med Res, 2008,39 ( 6 ) : 601-606.

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