阻塞性睡眠呼吸暂停低通气综合征与支气管哮喘关系的研究进展

The research progress of relationship between the obstructive sleep apnea hypopnea syndrome and asthma

阻塞性睡眠呼吸暂停低通气综合征（OSAHS）是睡眠期反复出现间断性的上气道阻塞引起以打鼾、呼吸暂停、呼吸浅慢、睡眠中断、低氧血症,以及日间嗜睡等为特征的临床综合征。支气管哮喘是由多种细胞和细胞组分参与的气道慢性炎症性疾病,

Obstructive sleep apnea hypopnea syndrome（OSAHS）is characterized by repeated episodes of upper airway obstruction that results in brief periods of breathing cessation（apnea）or a marked reduction in airflow（hypopnea）during sleep.Asthma is a chronic inflammatory disease of the airways characterized by revesible airflow obstruction and bronchial hyperresponsiveness.This article reviewed related reseaches progress of relationship between the obstructive sleep apnea hypopnea syndrom and asthma in the vascular endothelial growth factor,systemic inflammation,leptin,obesity,gastroesophageal reflux disease and upper airway diseases,excessive daytime sleepiness and asthma control.