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应关注帕金森病相关疼痛的研究 被引量：4

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摘要 由于多巴胺能药物的不断涌现,帕金森病（PD）的大部分运动症状能得到良好的控制,但仍然有很多的问题困扰着我们,直接影响患者的生活质量与工作能力.最近Deane等[1]对PD患者、医生、护理人员进行的调查显示,在等待根治或有效治疗的时候,需要开展的排名前十的研究中,首位是解决平衡问题,其次是减少患者的焦虑和抑郁,而减少运动并发症仅排在第三位.尽管这是一个基于西方人群的调查,但这些问题同样是我们应该关注的.在筛选出的26个被关注的问题中仅仅30％是运动症状相关的问题,更多的是非运动症状,包括认知、睡眠障碍、自主神经功能障碍、胃肠道症状、疼痛等,这些非运动症状不但有较高的发生率,而且可出现在疾病初期,伴随在PD进展的整个过程中,甚至出现在PD运动症状出现之前,有时可成为影响患者生活质量的主要原因.而其中合并的疼痛在临床未被重视,在早期还常常是导致诊断延误的重要原因.
作者 刘春风 毛成洁
机构地区 苏州大学附属第二医院神经内科
出处 《中华医学杂志》 CAS CSCD 北大核心 2015年第7期481-482,共2页 National Medical Journal of China
基金 江苏省临床医学科技专项（BL2014042） 苏州市临床重点病种诊疗技术专项（LCZX201304） 苏州市科技发展计划（SZS201205）
关键词 帕金森病 疼痛 非运动症状 运动并发症 自主神经功能障碍 多巴胺能药物 生活质量 胃肠道症状
分类号 R742.5 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献20

  • 1Deane KH, Flaherty H, Daley DJ, et al. Priority setting partnership to identify the top 10 research priorities for the management of Parkinson' s disease [ J ] . BMJ Open, 2014, 4 (12) : e006434.
  • 2Broen MP, Braaksma MM, Patijn J, et al. Prevalence of pain in Parkinson's disease: a systematic review using the modified QUADAS tool [ J ]. Mov Disord, 2012, 27 (4) :480-484.
  • 3张晓艺,毛成洁,陈怡,胡伟东,李洁,刘春风.帕金森病伴疼痛患者临床特征及认知功能研究[J].中华内科杂志,2014,53(1):27-30. 被引量：14
  • 4Silva EG, Viana MA, Quagliato EM. Pain in Parkinson's disease: analysis of 50 cases in a clinic of movement disorders [ J ]. Arq Neuropsiquiatr, 2008, 66( 1 ) :26-29.
  • 5Ngre-Pags L, Regragui W, Bouhassira D, et al. Chronic pain in Parkinson's disease: the cross-sectional French DoPaMiP survey [ J ]. Mov Disord, 2008, 23 (10) : 1361-1369.
  • 6Ford B. Pain in Parkinson's disease[J]. Mov Disord, 2010, 25 Suppl 1 :$98-103.
  • 7Scherder EJ, Sergeant JA, Swaab DF. Pain processing in dementia and its relation to neuropathology [ J ]. Lancet Neurol, 2003, 2 ( 11 ) :677-686.
  • 8Gerdelat-Mas A, Simonetta-Moreau M, Thalamas C, et al. Levodopa raises objective pain threshold in Parkinson's disease: a R m reflex study [ J ]. J Neurol Neurosurg Psychiatry, 2007, 78 (10) : 1140-1142.
  • 9Tinazzi M, Del Vesco C, Defazio G, et al. Abnormal processing of the nociceptive input in Parkinson's disease: a study with CO2 laser evoked potentials [ J ]. Pain, 2008, 136 ( 1-2 ) : 117-124.
  • 10Donadio V, Incensi A, Leta V, et al. Skin nerve c-synuclein deposits: a biomarker for idiopathic Parkinson disease [J]. Neurology, 2014, 82 ( 15 ) : 1362-1369.

二级参考文献19

  • 1中华医学会神经病学分会帕金森病及运动障碍学组.中国帕金森病治疗指南(第二版)[J].中华神经科杂志,2009,42:352-355.
  • 2Olanow CW,Stern MB,Sethi K. The scientific and clinical basis for the treatment of Parkinson disease(2009)[J].{H}NEUROLOGY,2009,(Suppl 4):S1-136.
  • 3Ford B. Pain in Parkinson's disease[J].{H}Clinical Neuroscience,1998.63-72.
  • 4Hughes A J,Daniel SE,Kilford L. Accuracy of clinical diagnosis of idiopathic Parkinson's disease:a clinico-pathological study of 100 cases[J].{H}JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY,1992.181-184.
  • 5Buysse DJ,Reynolds CF 3rd,Monk TH. The Pittsburgh Sleep Quality Index:a new instrument for psychiatric practice and research[J].{H}Psychiatry Research,1989.193-213.
  • 6Fitzpatrick R,Peto V,Jenkinson C. Health-related quality of life in Parkinson's disease:a study of outpatient clinic attenders[J].{H}Movement Disorders,1997.916-922.
  • 7Beiske AG,Loge JH,Ronningen A. Pain in Parkinson's disease:Prevalence and characteristics[J].{H}PAIN,2009.173.
  • 8Defazio G,Berardelli A,Fabbrini G. Pain as a nonmotor symptom of Parkinson disease:evidence from a case-control study[J].{H}Archives of Neurology,2008.1191-1194.
  • 9Stamey W,Davidson A,Jankovic J. Shoulder pain:a presenting symptom of Parkinson disease[J].{H}Journal of Clinical Rheumatology,2008.253-254.
  • 10Canavero S. Central pain and Parkinson disease[J].{H}Archives of Neurology,2009.282-283.

共引文献19

同被引文献36

  • 1Wu Q, Chen L, Zheng Y, et al. Cognitive impairment is common in parkinson: disease without dementia in he early and middle stages in a Han Chinese cohort[ J]. Parkinsonism & Related Disorders, 2012,18(2) :161 -165.
  • 2Kudlicka A,Clare L, Hindle JV. Executive functions in parkinson" s disease: systematic review and meta-analysis[ J]. Movement Dis- orders,2011,26( 13 ) :2305 - 2315.
  • 3Williams-Gray CH, Evans JR, Goris A, et al. The distinct cognitive syndromes of parkinson Js disease:5 year follow-up of the Cam- PaiGN cohort [ J ]. Brain,2009,132 ( Pt 11 ) :2958 - 2969.
  • 4Beyer MK, Bronnick KS, Hwang KS,et al. Verbal memory is asso-ciated with structural hippocampal changes in newly diagnosed parkinsong disease [J]. Journal of Neurology, Neurosurgery, and Psychiatry ,2013,84( 1 ) :23 -28.
  • 5Zhou S, Chen X, Wang C, et al. Selective attention deficits in early and moderate stage parkinsong disease[ J]. Neuroscience Letters, 2012,509 ( 1 ) :50 - 55.
  • 6Tomlinson CL, Stowe R, Patel S, et al. Systematic review of levodo- pa dose equivalency reporting in Parkinson "s disease [J]. Move- ment Disorders ,2010,25 ( 15 ) :2649 - 2653.
  • 7Lin CH, Wu RM. Biomarkers of cognitive decline in parkinson's disease [ J ]. Parkinsonism & Related Disorders, 2015,21 (5) : 431 -443.
  • 8Christensen JA, Nikolie M, Warby SC, et al. Sleep spindle altera- tions in patients with parkinsong disease[ J]. Frontiers in Human Neuroseienee ,2015,9:233.
  • 9Fasano A,Visanji NP,Liu LW,et al. Gastrointestinal dysfunction in parkinsong disease [ J ]. The Lancet Neurology, 2015,14 ( 6 ) : 625 - 639.
  • 10Roca M, Torralva T, Gleichgerrcht E, et al. Impairments in social cognition in early medicated and unmedica-ted parkinson disease [J]. Cognitive and Behavioral Neurology, 2010,23 (3):152 - 158.

引证文献4

二级引证文献21

中华医学杂志
2015年 第7期

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