摘要
目的研究小半夏加茯苓汤的化学成分。方法利用硅胶、反相硅胶柱、薄层色谱和重结晶等方法对小半夏加茯苓汤进行分离、纯化,通过波谱数据对化合物进行结构解析。结果从小半夏加茯苓汤中分离纯化得到5个化合物,分别鉴定为6-Shogaol黄酮(1)、Kaempferol黄酮醇(2)、Leucine氨基酸(3)、β-sitosterol甾醇(4)、Guanosine嘌呤核苷(5)。结论化合物1~5均首次从小半夏加茯苓汤中得到。
Objective To study the chemical constituents of Xiaobanxia- Fuling Decoction. Methods To Isolate and purify Xiaobanxia- Fuling Decoction by a combination of silica gel,ODS,TLC and recrystallization,then analyze the structure of its compounds by spectral data. Results We got five compounds by isolating and purifying Xiaobanxia- Fuling Decoction,which were identified as 6- Shogaol( 1),Kaempferol( 2),Leucine( 3),β- sitosterol( 4),guanosine( 5). Conclusion Compounds 1-5were isolated from Xiaobanxia- Fuling Decoction for the first time.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2015年第3期563-564,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金(No.30960472/C190105)
贵州省中药现代化专项研究课题(黔科合社字[2008]5025号)
关键词
小半夏加茯苓汤
黄酮
甾醇
嘌呤核苷
Xiaobanxia-Fuling Decoction
6-Shogaol
β-sitosterol
Guanosine