3D T1-VIBE序列用于评价强直性脊柱炎骶髂关节软骨的初步研究

Preliminary Study of 3D T1-VIBE Sequence for the Sacroiliac Joint Cartilage Imaging in Patients with Ankylosing Spondylitis

目的采用三维容积内插体部扫描序列(3D T1-VIBE)对强直性脊柱炎(AS)患者骶髂关节(SIJ)软骨进行扫描,分析其MRI表现,探讨3D T1-VIBE序列显示SIJ软骨的可行性。方法利用3D T1-VIBE序列对10名AS患者共20侧SIJ软骨进行MR扫描,着重观察SIJ软骨。结果 10例中3例髂侧关节软骨边缘模糊,部分层面可见SIJ软骨二者间隙;7例显示关节面模糊,不能区分出骶侧与髂侧关节软骨及其二者间隙,关节软骨侵蚀破坏、连续性中断。结论 3D T1-VIBE序列能较X线和CT更好显示AS患者SIJ软骨的侵蚀破坏,髂侧关节软骨的模糊、微侵蚀和关节软骨间隙消失是诊断早期骶髂关节炎(SIS)的重要征象。

Objective The purpose of the study was to evaluate the feasibility and application value of MR 3D T1-Weighted Gradient-Echo Imaging with a volumetric interpolated breath-hold examination （3D T1WI-VIBE） in the evaluation of joint cartilage of SIJ in patients with ankylosing spondylitis. Methods A total of 10 AS patients were collected randomly and the 3D T1-VIBE were performed for sacroiliac joint. MR manifestation of sacroiliac articular cartilage of 10 cases of ankylosing spondylitis patients were observed. Results 3D T1-VIBE sequence were performed in 10 patients （20 SIJs） with ankylosing spondylitis, blur iliac side edge of articular cartilage were showed in 3 cases. The gap between cartilage in the sacral and iliac side become unclear and even disappear, seven of ten articular cartilage shown erosion damage, discontinuous change. Conclusions 3D T1-VIBE can show the destroy and break of the articular cartilage in patients of AS. 3D T1-VIBE is a valuable technique for examination of articular cartilage of SIJ, which provides more information for clinic than X-ray and CT.