摘要
目的:探讨睾丸非精原细胞瘤(NSGCT)综合治疗的临床疗效以及辅助治疗方法。方法:回顾分析1999年5月~2008年12月近10年间在我院治疗的80例睾丸Ⅰ期NSGCT患者的临床资料,应用SPSS16.0统计软件包进行统计学分析,比较不同治疗方法与预后的关系。结果:生存分析显示腹膜后淋巴结清扫组与观察组差异有统计学意义(P=0.027);化疗组预后较观察组好,腹膜后淋巴结清扫组与化疗组差异无统计学意义(P=0.660)。结论:临床Ⅰ期NSGCT在睾丸根治术后建议行腹膜后淋巴结清扫术,其次是辅助化疗;无高危复发因素、依从性好的患者可选择密切随访。
Objective:To explore the experience in the multitreatment of nonseminomatous germ cell tumor(NSGCT)of testis.Method:Clinical data of 80 patients with stageⅠ NSGCT of testis undergoing multi-disciplinary approach at Cancer Center of Sun Yat-Sen University were retrospectively analyzed from 1999 to 2008.The prognosis of different groups according to clinical stage was evaluated.The statistics modal is Kaplan-Meier methods.Result:There were 80 patients with stageⅠ nonseminoma.The disease-free survival in patients undergoing retroperitoneal lymph node dissection(RPLND)was higher than those surveillance(P=0.027).The relapse-free survival curves of RPLND group and chemotherapy group had no significantly statistical difference(P=0.660).Conclusion:The recommended treatment for stageⅠ nonseminoma after orchidectomy is RPLND and chemotherapy.Close surveillance is also a management option to patients without high risk of recurrence and with good compliance.
出处
《临床泌尿外科杂志》
2015年第3期241-244,248,共5页
Journal of Clinical Urology