天津市公安民警颈动脉内中膜厚度与代谢综合征的关系

Correlation of carotid intima-media thickness and metabolic syndrome in Tianjin city policemen

目的分析天津市警察人群颈动脉内中膜厚度与代谢综合征(MS)的关系,探讨颈动脉内中膜增厚的危险因素。方法在体检警察人群中筛选出50例MS患者为MS组及50例健康体检者为对照组,对其进行问卷调查(家族史、既往史、现病史、生活习惯、职业紧张因素等);检测相关血液指标(空腹血糖、三酰甘油、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、同型半胱氨酸等);应用彩超测量其颈动脉内中膜厚度,计算颈动脉内中膜增厚比率;比较2组的相关指标,用Logistic回归模型分析颈动脉内中膜增厚的影响因素。结果 MS组的双侧颈总动脉、颈内动脉、颈外动脉内中膜厚度及内中膜增厚比率均高于对照组;高血压家族史、应激事件、现吸烟、糖尿病家族史、高脂饮食、高同型半胱氨酸血症是颈动脉内中膜增厚的危险因素,饮用奶制品是其保护因素。结论颈动脉内中膜增厚的原因具多样性,健康的生活方式及采取临床干预措施减缓颈动脉内中膜增厚,有利于控制动脉粥样硬化。

Objective To analyze the relationship between carotid intima-media thickness （CIMT） and metabolic syn-drome （MS）, and explore risk factors for CIMT incrassation in Tianjin policemen. Methods Fifty MS patients （MS group） and 50 healthy people （control group） in health examination of Tianjin policemen were enrolled in this study. The question-naire survey（family history,past medical history,present history,living habits and occupational stress factors） were recorded in two groups of patients. The blood indicators （fasting plasma glucose, triglycerides, total cholesterol, high density lipopro-tein cholesterol, low density lipoprotein cholesterol, homocysteine） were detected. The color Doppler was used to measure CIMT incrassation, and incrassation ratio was calculated. The relative indicators were compared between two groups. The lo-gistic regression model was used to analyse the influencing factors of carotid artery intima-media thickness. Results CIMT and CIMT incrassation ratio （communis, internal and external carotid） were significantly higher in MS group than those of control group （P〈0.01）. The risk factors for CIMT included family history of hypertension, chronic stress, smoking, family history of diabetes, high fat diet and high homocysteine levels, and dairy products were protective factors for CIMT incrassa-tion. Conclusion The reason of carotid artery intima-media thickness is diversity. The healthy lifestyle and clinical inter-vention to retard CIMT are advocate, which are conducive to the control of atherosclerosis.