自噬与肿瘤研究现状

Research progress of autophagy and tumor

自噬对肿瘤的发生发展起抑制和促进双重作用,且能决定某些肿瘤的发展方向;通过激活或抑制自噬能达到肿瘤治疗效果。通过调控自噬,有可能成为肿瘤治疗的新靶点。

Autophagy has a dual role of suppression and promotion in tumor genesis and progression,and autophagy can dictate the development direction of some tumor. It have achieved tumor treatment effect by activating or inhibiting autophagy. So it may become a new target for tumor therapy by regulating autophagy.