摘要
体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)及其衍生技术的最终目的是使不孕不育患者成功妊娠,其关键环节是胚胎成功着床。但目前辅助生殖中反复着床失败(recurrent implantation failure,RIF)发生率仍较高,且其发生原因并不明确,研究已发现其影响因素多而复杂。本文分析和综述RIF发生的原因及机制,以期从中总结出经验,提高辅助生殖临床胚胎着床率和妊娠率,从而改善辅助生殖临床中反复着床失败患者的预后。
The purpose of IVF-ET and its derivative technology is to make infertility patients get successful pregnancy,the key link is successful embryonic implantation. But the failure rate of recurrent implantation failure（RIF）in the assisted reproductive is still high,and studies have found that its reason is not clear and its influence factors is complicated. This article analyzes the reason and mechanism of RIF to summarize the experience so that improve clinical embryo implantation rate and pregnancy rate in the assisted reproduction. The ultimate goal is to improve the clinical prognosis of RIF patients in assisted reproduction.
出处
《中国优生与遗传杂志》
2015年第2期128-130,共3页
Chinese Journal of Birth Health & Heredity
基金
国家自然科学基金面上项目(81370710)
陕西省统筹创新项目(2013KTCL03-07)
关键词
反复着床失败
内膜容受性
胚胎
体外受精
Recurrent implantation failure
Endometrial receptivity
Embryos
In vitro fertilization
