石家庄市医务人员脂肪肝患病趋势及相关危险因素研究

Prevalence of fatty liver and risk factors among medical staffs in general hospitals of Shijiazhuang

目的明确石家庄市医务人员脂肪肝(fattyliver,FL)患病趋势、相关危险因素及其与代谢综合征其他组分的关系。方法回顾性分析河北医科大学第三医院体检中心1 428例石家庄市综合医院医务人员体检信息,根据性别、年龄、体质量指数(body mass index,BMI)、实验室检查及腹部超声检查结果分析FL患病情况及其与代谢综合征其他组分的关系。结果 FL患病率于70岁前随年龄增长呈递增趋势;60岁前男性明显高于女性(x^2=185.787,P<0.01)。Logistic回归分析显示性别、年龄、BMI、收缩压、舒张压、空腹血糖、总胆固醇、三酰甘油是FL的危险因素。结论石家庄市区综合医院医务人员FL患病率显著高于普通人群,其发病与BMI、空腹血糖、三酰甘油水平相关,其中BMI为FL患病或康复的预测因素。

Objective To investigate the prevalence and risk factors of fatty liver（FL）,and clarify the relationship between FL and other components of metabolic syndrome among medical staffs in the general hospitals of Shijiazhuang.Methods A retrospective study was performed to analyze the prevalence and related risk factors of FL in 1 428 medical stuffs who continuously participated in health examination in the Third Hospital of Hebei Medical University.Background variables for the analysis included gender,age,body mass index（BMI）,laboratory tests and abdominal ultrasound examination.Results The FL prevalence was increasing with age before 70 years old and higher in male than female among the participants younger than 60 years old（χ2 =185.787,P〈0.01）.Logistic multivariant regression analysis indicated that the incidence of FL was correlated to gender,age,BMI,systolic pressure,diastolic blood pressure,fasting blood sugar,total cholesterol and triglycerides.Conclusion There is a high incidence of FL in the medical staffs of general hospitals of Shijiazhuang,and BMI,blood glucose and triglycerides correlated with FL prevalence.BMI is an independent predictor for morbidity and recovery of FL.