78例新生儿吸入性肺炎的临床诊疗分析

Analysis on clinical characteristics,diagnosis,and treatment of 78 cases with neonatal aspiration pneumonia

目的观察新生儿吸入性肺炎的临床特点和治疗效果。方法将新生儿吸入性肺炎患儿78例随机分为A组(常规抗生素+盐酸氨溴索组)、B组(常规抗生素+盐酸氨溴索+布地奈德组)、C组(常规抗生素治疗组)各26例。治疗7 d后比较3组患儿的疗效,分析总有效率、临床症状、不良反应发生情况。结果 A组总有效率为92.31%,B组总有效率为96.15%,C组总有效率为76.92%。3组总有效率比较差异无统计学意义。A、B组呼吸困难、紫绀、肺部啰音等症状消失时间早于C组、住院时间少于C组,尤其是B组与C组治疗效果比较,B组具有一定的优势。结论盐酸氨溴索和布地奈德的使用可以改善患儿的临床症状,用药安全可靠,有利于患儿早日康复。

Objective To explore the clinical characteristics and curative effect of neonatal aspiration pneumonia.Methods Seventy-eight cases with neonatal aspiration pneumonia were randomly divided into three groups,each group 26 patients,C group with conventional treatment of neonatal aspiration pneumonia,A group with ambroxol hydrochloride on the basis of C group,and B group with budesonide and ambroxol hydrochloride treatment on the basis of C group.The total efficiency,the clinical symptoms and signs disappeared time,hospital stay,the incidence of adverse reactions of three groups were compared after seven days of treatment.Results The total efficiency in A group（92.31%）and B group（96.15%）were higher than that in C group（76.92%）.The difference were statistically significant among three groups（P〈0.05）.Breathing difficulty disappeared time,Cyanosis disappeared time and lung rale disappeared time of A group and B group ware earlier than those of C group.And the effect of B group was better than C group.Conclusion Ambroxol（A group）or budesonide jointed ambroxol（B group） in the treatment of neonatal aspiration pneumonia has achieved better clinical results,and improved the clinical signs and symptoms,the medication is safe and reliable,which will help the quick recovery of the children.