168例急性下肢深静脉血栓治疗的疗效比较

The Clinical Effect Comparison of Treatment for 168 Cases with Acute Lower Extremity Deep Venous Thrombosis

比较单纯抗凝与深静脉置管溶栓治疗168例急性混合型下肢深静脉血栓形成（LEDVT）患者的近期疗效、随访疗效与并发症。回顾性分析2011年1月至2013年12月辽宁省人民薮院收治的168例急性混合型LEDVT病例，分为单纯抗凝组（A组，78例）和深静脉置管溶栓组（B组，90例），对两组近期、随访12个月～24个月的总有效率、治愈率、健患肢周径差、静脉通畅率、并发症进行比较。结果近期、随访12个月～24个月的总有效率、治愈率。健患肢周径差、静脉通畅率，B组均优于A组（P〈0．05）；治疗期间出血并发症B组与A组无差异；随访12个月～24个月血栓后综合征（PTS）发生率，B组明显低于A组（P〈0.05）。深静脉置管溶栓疗效确切，不良反应小，可提高静脉通畅率及降低PTS发生率，值得临床推广。

To compare the clinical effect and complication （CDT） of acute lower extremity deep venous thrombosis about puring anticoagulation and catheter directed thrombolysis （LEDVT） of mixed type. The clinical data of 168 patients with acute lower extremity deep venous thrombosis of mixed type from January 2011 to December 2013 were analyzed retrospectively. 168 LEDVT cases were divided into two groups： puring amicoagulation group （Group A,78 cases） and CDT group （Group B,00 cases）, to make a comparative analysis on the total effective rate, cure rate, lower extremity circumference change, blood vessel patency rate and complication before and after treatment of group A and group B. During hospitalization, the 12 months - 24 months after treatment, total effective rate, cure rate, lower extremity circumference change, blood vessel patency race in the group B was superior to the group A （P〈0. 05）. The incidence of bleeding had no significant difference. The incidence of post thrombotic syndrome （PTS） in the group B was lower than the group A in the 12 mouths follow-up. CDT is safe and effective for acute LEDVT. It can increase lower extremity deep vein patency and reduce the risk of PTS, worthy of the clinical popularize.