膀胱癌相关基因的研究现状与展望

Progress in Resarches and Prospects of Bladder Cancer Associated Genes

膀胱癌是我国最为常见的一种泌尿系统肿瘤,其预后较差。肿瘤的发生发展是一个较为复杂的过程。膀胱癌相关基因的研究能够提高该病早期诊断、治疗的敏感性及特异性,并可以此靶标来寻找新的抗肿瘤药物和方法,并为最终攻克膀胱癌这一顽疾提供了强有力的理论支撑,具有划时代的意义。目前已经发现了许多膀胱癌相关基因,笔者复习大量国内外相关文献报道,旨对该领域的研究进展进行综述。

Bladder cancer is one of the most common malignant tumors in the urinary system, and usually has bad prognosis. The occurrence and development of bladder cancer is very complicated. The study on the associated genes of bladder cancer can improve the sensitivity and specificity of early diagnosis and treatment of bladder cancer, and can also be used target frame for searching antitumor drugs methods, and provide the foundation for conquering bladder cancer, it has epoch-making significance. Currently many bladder cancer associated with genes have been found. The authors reviewed a large amount of relevant articles, in order to summarize the status of current studies in this field.