摘要
目的研究河南省南阳市2012-2014年手足口病流行期间健康人群肠道病毒(Enterovirus,EV)感染状况。方法采用体外反转录-聚合酶链反应(reverse transcriptase-polymerase chain reaction,RT-PCR),对南阳市2012 2014年分离自健康人群的EV进行核酸检测。调查对象共分为10个年龄组,每组10人,每年调查100人,每人均采集粪便和咽拭子标本。结果在连续3年流行期监测的300名健康人群中,肠道病毒感染率为42.67%。≤5岁儿童为主要感染人群,性别分布差异无统计学意义(χ2=0.587,P>0.05)。结论肠道病毒在健康人群中分布普遍,以其他EV为主,未检出肠道病毒71型和柯萨奇病毒A组16型。
Objective To understand the infection status of enterovirus in healthy population during hand foot and mouth disease (HEMD) epidemic period in Nanyang, Henan province. Methods From 2012 to 2014, 100 healthy people in 10 age groups were selected each year, and reverse transcriptase-polymerase chain reaction (RT-PCR) was conducted to detect nucleic acid of enterovirus isolated from the stool samples and throat swabs collected from them. Results Among the 300 healthy people, the EV infection rate was 42. 67%. Children aged 〈 5 years were mainly affected. The difference in infection rate between males and females had no statistical significance (X^2 = 0. 587, P 〉 0. 05). No EV71 and Cox A16 were detected. Conclusion Enterovirus is widely distributed in healthy population.
出处
《疾病监测》
CAS
2015年第1期27-29,共3页
Disease Surveillance
关键词
手足口病
健康人群
肠道病毒感染
Hand foot and mouth disease
Healthy population
Enterovirus infection