匹多莫德辅助治疗小儿反复呼吸道感染的效果及对患儿免疫功能的影响

Effect of pidotimod auxiliarily treating recurrent respiratory tract infection in children and the influence of pidotimod on immune function of ill children

目的：探讨匹多莫德辅助治疗小儿反复呼吸道感染的的效果及可能的机制。方法将2012年9月-2013年9月本院收治的120例反复呼吸道感染患儿随机均分为观察组和对照组，对照组给予常规治疗，观察组在常规治疗的基础上给予匹多莫德片口服治疗。比较两组的疗效及CD3、CD4、CD8水平。结果观察组的总有效率为88.3%，明显高于对照组的73.3%（P〈0.05）；治疗8周后，观察组的CD3、CD4、CD8水平较对照组改善更显著（P〈0.05）。结论匹多莫德辅助治疗反复呼吸道感染的效果确切，能够提高患儿的免疫水平。

Objective To explore the effect of pidotimod auxiliarily treating recurrent respiratory tract infection in chil-dren and possible mechanism. Methods 120 children with recurrent respiratory tract infection treated in our hospital from September 2012 to September 2013 were randomly and evenly divided into the observation group and control group.The control group was given conventional therapy, and the observation group was given oral pidotimod based on conventional therapy,the curative effect and CD3,CD4,CD8 level in the two groups were compared. Results The total effective rate of the observation group was （88.3%） was evidently higher than that in the control group （73.3%）（P〈0.05）;after 8 weeks treatmentthe CD3,CD4,CD8 level were obviously improved in the observation group compared with the control group （P〈0.05）. Conclusion Pidotimod has an exact effect treating recurrent respiratory tract infection in children,and can improve the immune level of ill children.