甲状腺结节合并微钙化与甲状腺癌关系及其危险因素分析

Analysis of correlation and risk factors between thyroid nodules with microcalcification and thyroid cancer

目的:探讨甲状腺结节合并微钙化与甲状腺癌的相关性及其危险因素,为甲状腺癌的早期诊断提供帮助。方法:选择526例甲状腺结节患者,分析良性结节、恶性结节的钙化类型及比例,并分析甲状腺结节合并微钙化的危险因素。结果:526例术前B超诊断为甲状腺结节患者中,术后病理确诊为甲状腺恶性肿瘤者148例。良性结节微钙化率较低;恶性结节微钙化率为52.7%,其独立危险因素为年龄≥45岁、单发结节、血流丰富、颈部淋巴结肿大。结论:对于经B超诊断为甲状腺结节的患者,应综合评估其临床特征,若年龄≥45岁、单发结节、微钙化、血流丰富且伴颈部淋巴结肿大者高度警惕甲状腺癌,此时可考虑手术进行病理确诊,及时治疗以改善患者预后。

Objective： To investigate the correlation and risk factors between thyroid nodules with micro calcification and thyroidcancer,to provide helpness for early diagnosis of thyroid cancer. Methods： 526 patients with thyroid nodules,the calcification type and proportion in benign nodules or malignant nodules were analyzed,and the risk factors of thyroid nodules associated with microcalcification were analyzed. Results： Amomg 526 patients with thyroid nodule who were diagnosised by preoperative B ultrasound,there were 148 cases who were diagnosised as thyroid malignant tumor by postoperative pathology. The microcalcification rate in benign nodules was low. The microcalcification rate of malignant nodules was 52. 7%,its independent risk factors were above 45 years old,solitary nodule,rich blood flow and cervical lymph node enlargement. Conclusion： To the patient who is diagnosised as thyroid nodules by B ultrasound,the clinical features should be evaluated,if his or her age is above45 years old,nodule is solitary nodule,calcification focus is microcalcification,rich blood flow and cervical lymph node enlargement,the thyroid nodules may very likely be thyroid cancer. At this moment foroperation pathology diagnosis can be considered to be done,it can improve patient＇s prognosis by timely treatment.