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啮齿类动物抑郁症模型的行为学检测方法 被引量:13

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摘要 抑郁症是以显著而持续的情绪低落为主要临床特征的一种精神异质性综合征。它是世界范围十大高发病率和病死率疾病之一。抑郁症的诊断主要以临床症状为主。因此,在针对抑郁症的动物研究中,抑郁行为学检测指标在鉴定模型复制以及抗抑郁药物疗效方面起重要作用。
出处 《河北医科大学学报》 CAS 2015年第3期370-372,共3页 Journal of Hebei Medical University
基金 国家重点基础研究发展计划(2013CB531302)
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  • 1Lukas M, Toth I, Reber SO, et al.The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice [J ]. Neuropsychopharmacology, 2011,36 ( 11 ) : 2159-Z168.
  • 2Ramanathan M, Balaji B, Justin A. Behavioural and neurochemical evaluation of perment an herbal formulation in chronic unpredictable mild stress induced depressive model [J].lndian J Exp Biol,2011,49(4) :269-275.
  • 3Chaudhury D, Walsh J J, Friedman AK, et al. Rapid regulation of depression related behaviours by control of midbrain dopamine neurons [J].Nature,2013,493(7433):532-536.
  • 4Borges S, Coimbra B, Soares-Cunha C, et al. Dopaminergic modulation of affective and social deficits induced by prenatal glucocorticoid exposureFJ]. Neuropsychopharmacology, 2013, 38(10) :2068-2079.
  • 5Dimatelis J J, Stein DJ, Russell VA. Behavioral changes after maternal separation-are reversed by chronic constant light treatment[J]. Brain Res, 2012,1480 : 61 - 71.
  • 6Yu P, Wang J, Tai F, et al. The effects of repeated early deprivation on ultrasonic vocalizations and ontogenetic development in mandarin vole pups [J]. Behav Processes, 2011,88(3) : 162- 167.
  • 7Taksande BG,Faldu DS,Dixit MP,et al.Agmatine attenuates chronic unpredictable mild stress induced behavioral alteration in mice[J].Eur J Pharmacol,2013,720(1/3) :115-120.
  • 8Ifiiguez SD, Riggs LM, Nieto SJ, et al. Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice[J].Stress,2014,17(3) :247-255.
  • 9Hollis F, Duclot F, Gunjan A, et al. Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus[J].Horm Behav, 2011,59(3) : 331- 337.
  • 10Bowens N, Heydendael W, Bhatnagar S, et al. Lack ofelevations in glucocorticoids correlates with dysphoria-like behavior after repeated social defeat[J 3. Physiol Behav, 2012, 105(4) :958-965.

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