精神分裂症住院患者辅助治疗药物的使用分析

Analysis on Ancillary Drugs Used in Inpatients with Schizophrenia

目的:了解长期住院精神分裂症患者辅助药物使用情况。方法:在1年内均匀截取3个时点(2013-10-20、2014-04-20、2014-10-20),对广州市民政局精神病院长期住院使用抗精神病药治疗的精神分裂症患者处方进行调查分析。结果:3个时点使用抗精神病治疗的患者分别为635、680、774例,合用辅助药物的患者分别占比91.97%、91.76%、91.73%,其中护肝药使用率分别为55.12%、36.18%、57.88%,心血管系统用药使用率分别为52.00%、50.44%、42.76%。结论:辅助用药情况可反映出肝脏损害和心血管系统疾病是抗精神病常见不良反应,中药制剂为长期治疗并减轻其不良反应的有效手段。

Objective To understand the usage of the ancillary drugs in long-term inpatients with Schizophrenia. MethodsPrescriptions of long-term inpatient with Schizophrenia who used antipsychotic were analyzed,within a year of uniform section from 3 time points（October 20,2013,April 20,2014,October 20,2014）. Results There were 635,680 and 774 inpatients who used antipsychotic respectively in these 3 time points,and the percentage of patients combined with auxiliary drug was 91.97 %,91.76 % and 91.73 %,respectively. The usage of hepatoprotective drug was 55.12 %,36.18 % and 57.88 %,and the cardiovascular system drug was 52.00 %,50.44 % and 42.76 %,respectively. Conclusion The usage of auxiliary medication can refl ect the damage of liver and cardiovascular system disease,which is common adverse reaction of antipsychotic. Traditional Chinese medicine preparation is an effective means to alleviate the adverse reaction of long-term using antipsychotic.