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血清脂联素水平与子宫内膜癌的关系分析 被引量:3

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摘要 目的探讨血清脂联素水平与子宫内膜癌的临床关系。方法用酶联免疫法(ELISA法)检测50例子宫内膜癌患者(实验组)与50例健康女性(对照组)血清脂联素水平,分析血清脂联素水平与子宫内膜癌的关系。结果实验组患者平均血清脂联素水平[(4.36±1.24)mg/L]显著高于对照组[(15.33±2.48)mg/L](P<0.01);Ⅲ/Ⅳ期患者平均血清脂联素水平(4.09±1.93)mg/L,显著低于Ⅰ/Ⅱ期患者[(5.37±0.83)mg/L](P<0.05);肿瘤分化程度越高,血清脂联素水平越高;无淋巴结转移患者血清脂联素水平[(6.53±0.27)mg/L]显著高于有淋巴结转移患者血清脂联素水平[(4.05±0.84)mg/L](P<0.05);体内血清脂联素含量越低,患子宫内膜癌的风险越高(χ2=9.991,P<0.01,OR=0.851,95%CI为1.979,1.026,P<0.05)。结论血清脂联素水平在子宫内膜癌患者体内会降低,低水平血清脂联素是子宫内膜癌发生的独立危险因素。
作者 陈磊 陈萍
出处 《中国实用医药》 2015年第5期102-103,共2页 China Practical Medicine
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