乳腺神经内分泌癌的超声声像图表现及误诊原因分析

Sonographic Features of Breast Neuroendocrine Carcinoma and Analysis of Misdiagnosis

目的：探讨乳腺神经内分泌癌的超声声像图特征,分析误诊原因。方法：回顾性分析2006年11月—2014年2月在我院外科接受手术治疗并经病理证实的28例乳腺原发神经内分泌癌的声像图表现。结果：28例患者皆为女性,年龄43~77岁,平均58.8岁。超声检查共发现27例肿块,肿块直径7~30mm。超声肿块检出率96.4%,但恶性诊断敏感性仅为60.7%。声像图上,乳腺神经内分泌癌有3方面特征（有无钙化灶、后方回声、纵横比）主要符合良性肿块表现,1个方面的特征（内部回声）主要符合恶性肿块表现,另有3个方面特征（形态、边缘、内部血流）无特异性。结论：乳腺神经内分泌癌的声像图上部分偏向良性肿块、部分偏向恶性肿块的表现是造成误诊率较高的主要原因。

Purpose： To discuss sonographic features of breast neuroendocrine carcinoma （NEC）, in order to analyze the case of misdiagnosis. Methods： From Nov 2006 to Feb 2014, 28 cases of primary breast NEC patients confirmed by surgery pathological results were retrospective analyzed. Results： All 28 cases were female, age ranged from 43 to 77 years old （mean 58.8）. The tumor sizes were 7-30mm （mean 18.2±6.8mm） in diameter. Tumor detection rate of ultrasound was 96.4%, while malignancy diagnostic sensitivity of ultrasound was only 60.7%. Breast NEC showed three features （presence or absence of calcification, posterior echo, aspect ratio） were mainly consistent with benign masses, one feature （inner echo-texture） was mainly consistent with malignant masses, and other three features showed no specific. Conclusion： Higher ultrasound misdiagnosis rate of breast NEC was mainly due to its partial benign and partial malignant performance in ultrasound images.