腹腔镜残胃癌根治术空肠R型代胃 食管-空肠三角吻合技术的应用研究

Application of R-type jejunal interposition and esophagojejunostomy by delta- shaped anastomosis after totally laparoscopic radical gastrectomy for gastric stump carcinoma

目的：探讨空肠＂R＂型代胃、食管-空肠三角吻合技术在腹腔镜下残胃癌根治术中的应用及其近期疗效。方法：回顾性分析2013年1月至2014年8月于本院实施腹腔镜残胃癌根治术空肠＂R＂型代胃、食管-空肠三角吻合手术的10例残胃癌患者（腹腔镜组）的临床资料,并与同期18例行开腹手术残胃癌切除术的患者（开腹组）临床病例资料进行对比。对患者术中、术后情况,淋巴结清扫数目、术后并发症、住院日、营养状况等进行分析研究,术后随访14~21个月。结果：10例患者均成功手术,无中转开腹患者,与开腹组相比,平均手术时间（210.0±30.9）min vs.（283.9±50.9）min,平均术中出血量（90.0±26.7）m L vs.（277.8±79.1）m L,平均清扫淋巴结数目（19.0±3.6）枚vs.（18.8±3.7）枚,术后首次下床时间（17.3±3.6）h vs.（75.8±15.7）h,术后首次进流食时间（1.6±0.4）d vs.5.7±1.3）d,胃肠道功能恢复时间（3.0±0.8）d vs.（7.2±1.3）d,术后平均住院时间（7.6±1.2）d vs.（20.8±3.9）d,腹腔镜组所有患者术后均未出现吻合口狭窄、反流性食管炎、吻合口出血、吻合口瘘、倾倒综合征、肠梗阻等并发症,无围手术期死亡,均顺利出院。返院复查患者营养状况良好,无进食哽噎感、食管后烧灼感等不适症状。结论：空肠＂R＂型代胃、食管-空肠三角吻合技术在腹腔镜下残胃癌根治术中的应用是安全、可行的,可提高患者术后生活质量,具有较好的近期疗效,同时可以达到与开腹手术相同的根治效果。

Objective： To evaluate the short-term efficacy of R-type jejunal interposition and esophagojejunostomy by delta-shaped anastomosis after totally laparoscopic radical gastrectomy for gastric stump carcinoma. Methods：Data on 10 patients with gas-tric stump cancer were analyzed retrospectively from January 2013 to August 2014. All the patients received R-type jejunal interposi-tion and esophagojejunostomy by delta-shaped anastomosis after totally laparoscopic radical gastrectomy for gastric stump carcinoma （laparoscope group） in the Lanzhou General Hospital of the Lanzhou Military Area. Laparotomy was performed on 18 cases that com-prised the control group （laparotomy group）. The intraoperative and postoperative indicators between these two groups were then com-pared. All the patients were followed-up from 14 to 21 months after the operations. Results：The operations were successfully carried out in all 10 patients （laparoscope group）, without performing open operation. The mean operative times, volumes of the intraoperative blood loss, numbers of dissected lymph nodes, frequencies of leaving the bed, days marking the first liquid diet intake, days marking the recovery of gastrointestinal function, and days of hospitalization of the laparoscope group and the laparotomy group were （210.0 ＆#177; 30.9） min and （283.9 ＆#177; 50.9） min, （90.0 ＆#177; 26.7） mL and （277.8 ＆#177; 79.1） mL, （19.0 ＆#177; 3.6） and （18.8 ＆#177; 3.7）, （17.3 ＆#177; 3.6） h and （75.8 ＆#177; 15.7） h, （1.6 ＆#177; 0.4） d and （5.7 ＆#177; 1.3） d, （3.0 ＆#177; 0.8） d and （7.2 ＆#177; 1.3） d, and （7.6 ＆#177; 1.2） d and （20.8 ＆#177; 3.9） d, respectively. Anastomotic stricture, reflux esophagitis, bleeding, leakage, dumping syndrome, or intestinal obstruction was not detected in the laparoscope group. There was no perioperative death. All of the cases exhibited good nutrition situation, and no choking or esophagus burning was reported. Conclusion：R-type jejunal interposition and esophagojejunostomy by delta-shaped anastomosis after totally laparoscopic radical gastrectomy is safe and feasible. The operation can improve the quality of life of patients and induce positive short-term therapeutic effects. Laparo-scopic-assisted radical gastrectomy for gastric stump cancer has the same effect as laparotomy.