期刊文献+

间充质干细胞治疗视网膜疾病的潜能及影响因素 被引量:3

Therapeutic potential and influencing factors of mesenchymal stem cells on retinal diseases
下载PDF
导出
摘要 作为干细胞家族的一员,其对损伤组织的修复作用已得到证实。虽然具体作用机制尚不完全明确,在间充质干细胞治疗视网膜疾病中有巨大潜能。现阶段不同的实验所得的结果相差较大,对间充质干细胞的研究任重而道远。综合分析其可能的作用机制和影响因素,对进一步探索间充质干细胞有重要意义。 As a member of the stem cells family,mesenchymal stem cells( MSCs) have been proved to be effective on the repair of tissue injury. Although the specific mechanism is still unclear,MSCs do have a promising future in retinal disease therapy. The results of the current research are diverse. We still have an urgent and long way to explore the details of MSCs. So it's significant for further understanding of MSCs to analyze the possible mechanism and influencing factors.
出处 《国际眼科杂志》 CAS 2015年第3期459-463,共5页 International Eye Science
基金 国家自然科学基金(No.81271026) 福建省创新平台基金(No.2010Y2003)~~
关键词 间充质干细胞 视网膜疾病 移植 治疗 mesenchymal stem cell retinal diseases transplant therapy
  • 相关文献

参考文献3

二级参考文献15

  • 1ZHANG Jie1,2, SHAN Qing1, MA Ping1, JIANG Yanming1, CHEN Peng1, WEN Jingxia1, ZHOU You1, QIAN Huanwen1 & PEI Xuetao2 1. Beijing Institute of Radiation Medicine, Beijing 100850, China,2. Beijing Institute of Transfusion Medicine, Beijing 100850, China.Differentiation potential of bone marrow mesenchymal stem cells into retina in normal and laser-injured rat eye[J].Science China(Life Sciences),2004,47(3):241-250. 被引量:10
  • 2Almasieh M, Wilson AM, Morquette B, et al. The molecu- lar basis of retinal ganglion cell death in glaucoma [ J ]. Prog Retin Eye Res, 2012, 31: 152- 181.
  • 3Coorey NJ, Shen W, Chung SH, et al. The role of gila in retinal vascular disease [ J]. Clin Exp Optom, 2012, 95: 266 - 281.
  • 4Rich K A, Figueroa SL, Zhan Y, et al. Effects of Muller cell disruption on mouse photoreceptor cell development [J]. Exp Eye Res, 1995, 61:235-248.
  • 5Bringmann A and Wiedemann P, Muller glial cells in reti- nal disease [J]. Ophthalmologica, 2012, 227: 1- 19.
  • 6Bringmann A, Iandiev I, Pannicke T, et al. Cellular signa- ling and factors involved in Muller cell gliosis: neuroprotec- tive and detrimental effects [ J ]. Prog Retin Eye Res, 2009, 28 : 423 - 451.
  • 7Wurm A, Iandiev I, Uhlmann S, et al. Effects of ischemia- reperfusion on physiological properties of Muller glial cells in the porcine retina [ J]. Invest Ophthalmol Vis Sci, 2011, 52 : 3360 - 3367.
  • 8Ghosh F and Johansson K. Neuronal and glial alterations incomplex long-term rhegmatogenous retinal detachment [ J] Curt Eye Res, 2012, 37:704-711.
  • 9Bringmann A, Pannicke T, Biedermann B, et al. Role of retinal glial cells in neurotransmitter uptake and metabolism [ J]. Neuroehem Int, 2009, 54: 143- 160.
  • 10Martin K R, Levkovitch-Verbin H, Valenta D, et al. Reti- na] glutamate transporter changes in experimental glaucoma and after optic nerve transection "in the rat [ J]. Invest Oph- thalmol Vis Sci, 2002, 43 : 2236 - 2243.

共引文献4

同被引文献11

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部