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急性冠状动脉综合征患者血清卵泡抑素样蛋白1水平的变化及其临床意义 被引量：10

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摘要 目的通过测定急性冠状动脉综合征(ACS)患者和正常对照者血清卵泡抑素样蛋白1(FSTL1)水平,探讨ACS患者血清FSTL1水平检测的临床意义。方法选择ACS患者123例[不稳定型心绞痛43例(UAP组)、急性非ST段抬高型心肌梗死34例(NSTEMI组)、急性ST段抬高型心肌梗死46例(STEMI组)]、稳定型心绞痛患者25例(SAP组)及对照组30例(NC组),采用酶联免疫吸附法测定血清FSTL1并进行比较分析。结果 (1)NC组和SAP组患者血清FSTL1水平比较差异无统计学意义(P>0.05);ACS各组患者血清FSTL1水平比较差异无统计学意义(P>0.05),ACS各组患者血清FSTL1水平明显均高于NC组和SAP组,差异有统计学意义(P<0.01)。(2)ACS患者血清FSTL1水平越高,心血管事件发生率越高。(3)冠心病各组LDL-C水平与NC组比较差异均有统计学意义(P<0.05)。结论 ACS患者血清FSTL1水平明显升高,血清FSTL1水平检测对于ACS的辅助诊断、危险分层及预后评判等有一定临床价值。
作者 孙黎明 陈斌 周哲 朱映红 董政 汪明琅
机构地区 江苏省连云港市第二人民医院心内科
出处 《重庆医学》 CAS 北大核心 2015年第9期1256-1258,共3页 Chongqing medicine
基金 连云港市卫生局基金资助项目(1220)
关键词 急性冠状动脉综合征 卵泡抑素相关蛋白质类 冠心病
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献7

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共引文献12

同被引文献95

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引证文献10

二级引证文献52

重庆医学
2015年 第9期

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