重组人脑利钠肽治疗急性心肌梗死后心力衰竭临床研究

Clinical study on recombinant human brain natriuretic peptide in the treatment of acute myocardial infarction induced heart failure

目的探讨重组脑利钠肽(rh BNP)治疗急性心肌梗死后心力衰竭的临床效果。方法选择我院收治的急性心肌梗死后慢性心力衰竭患者80例,分为两组,各40例。观察组给予rh BNP治疗,对照组采取常规抗心衰治疗。对比观察两组患者的临床治疗效果。结果观察组治疗有效率显著高于对照组,差异显著(P<0.05)。观察组治疗后舒张压、收缩压、心率和左室射血分数均显著优于对照组,差异显著(P<0.05)。结论对于急性心肌梗死后心力衰竭患者采取rh BNP治疗具有显著的临床效果,值得临床大力推广。

Objective This article was to investigate the clinical effects of recombinant human brain natriuretic peptide （rhBNP） in the treatment of acute myocardial infarction induced heart failure. Methods Eighty patients, those who suffered acute myocardial infarction induced chronic heart failure and hospitalized in our hospital, were divided into two groups, forty eases in each group. Patients in the observation group were given rhBNP treatment, while patients in the control group adopted conventional anti heart failure treatment. The clinical efficacy of the two groups was observed. Results The effective rate of the observation group was significantly higher than the control group, the difference was statistically significant （P 〈 0. 05）. After been treated, diastolic and systolic blood pressure and heart rate and left ventrieular ejection fraction of observation group was significantly better than control group, the differences were statistically significant （ P 〈 0. 05 ）. Conclusions rhBNP was effective for patients suffered acute myocardia[ Key words ]