自拟中药方联合西医治疗糖尿病的临床疗效

Clinical Curative Effect of Self-made Herbal Medicine Combined with Western Medicine on Diabetes

目的:探讨自拟中药方剂联合西医治疗糖尿病患者的临床疗效。方法:选择本院糖尿病俱乐部参与的2型糖尿病患者70例,随机分为中西医结合组和西医组,每组35例,两组患者均给予非药物治疗方案,西医组在此基础上加用盐酸二甲双胍肠溶片、格列齐特片,中西医结合组在西医组基础上加用自拟中药方,治疗4周为一个疗程,两组均连续治疗3个疗程,比较两组患者治疗前后中医证候积分、空腹血糖(FBG)以及餐后2 h血糖(2h PG)、空腹胰岛素(FINS)以及餐后2 h胰岛素(2h INS)水平,观察两组患者治疗期间不良反应发生情况。结果:治疗后,中西医结合组中医证候积分显著优于对照组(P<0.05);治疗后,中西医结合组FBG、2h PG、FINS、2h INS水平均显著低于西医组(P<0.05);治疗期间,西医组不良反应发生了为17.14%、中西医结合组不良反应发生率为2.86%,两组比较,差异具有统计学意义(P<0.05)。结论:我院自拟中药方联合西医治疗糖尿病能够显著改善患者中医证候,有效控制患者血糖水平以及胰岛素水平,且能够显著降低药物有关不良反应发生率。

Objective： To investigate the clinical efficacy of self-made prescription of traditional Chinese medicine combined with western medicine in the treatment of patients with diabetes mellitus. Methods： 70 patients with type 2 diabetes mellitus patients in our hospital club participation,randomly divided into western medicine group and Western medicine group,35 cases in each group,two groups of patients were given non drug therapy,western medicine group based on the use of metformin hydrochloride enteric coated tablets,Gliclazide Tablets,group in Western Medicine Group on the basis of with Chinese herbal medicine combined with western medicine,treatment for 4 weeks for a course of treatment,two groups were treated for 3 courses of treatment,two groups were compared before and after treatment,compared two groups of patients with TCM syndromes,fasting blood glucose（FBG） and 2 h postprandial blood glucose（2h PG）,fasting insulin（FINS） and 2 h postprandial insulin（2h INS） levels were observed in two groups of patients,the occurrence of adverse reactions during. Results： after the treatment,the control group was significantly better than the combination of TCM Syndromes of traditional Chinese medicine and Western Medicine（P〈0.05）; integrated traditional Chinese and Western medicine group after treatment,FBG,2h PG,FINS,2h INS levels were significantly lower than those in the western medicine group（P〈0. 05）; during the treatment,western medicine group adverse reactions occurred in 17. 14%,the combination of Western medicine in drug adverse reaction rate of 2. 86%,the comparison between the two groups,the difference was statistically significant（P〈0. 05）. Conclusion： the treatment of diabetes in our hospital self-made herbal medicine combined with western medicine can significantly improve the patient symptom,effective control of blood glucose level and insulin levels,and can significantly reduce the incidence of adverse drug reactions.