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糖尿病合并非酒精性脂肪肝的危险因素分析 被引量:5

Risk factor analysis of type 2 diabetes mellitus with non-alcoholic fatty liver disease
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摘要 目的:探讨2型糖尿病合并非酒精性脂肪肝(NAFLD)的危险因素。方法:回顾性分析104例2型糖尿病合并NAFLD患者和157例未合并NAFLD糖尿病患者性别、年龄、糖尿病家族史、高血压病史、吸烟史、体重指数(BMI)、血尿酸、谷丙转氨酶、谷草转氨酶、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、超敏C反应蛋白、血浆凝血酶原时间(PT)、糖化血红蛋白(HBA1C)、空腹血糖(FPG)的差异。非条件logistic回归模型进行2型糖尿病合并NAFLD的危险因素分析。结果:2组年龄、BMI、HBA1C、FPG、TG差异有统计学意义(χ2=7.266、66.897、8.911、9.348、30.161,P〈0.05);Logistic回归模型分析结果显示肥胖、高TG是2型糖尿病合并NAFLD的危险因素[OR(95%CI)=4.503(2.930~6.919),1.563(1.154~2.117)]。结论:肥胖和高TG是2型糖尿病合并NAFLD的危险因素。 Aim: To investigate the risk factors of type 2 diabetes mellitus with non-alcoholic fatty liver disease ( NAFLD) .Methods:A total of 261 cases of type 2 mellitus diabetes were collected and allocated into 2 groups according to with or without NAFLD .The risk factors of type 2 mellitus diabetes with NAFLD were analyzed by using logistic regres-sion analysis.Results:The analysis of univariate factor showed that age ,BMI,HBA1C,FPG,TG had statistical significance between the 2 groups(χ2 =7.266,66.897,8.911,9.348,30.161,P〈0.05).Logistic regression analysis demonstrated that obesity and increased TG are dangerous factors of type 2 diabetes mellitus with NAFLD[OR(95%CI) =4.503 (2.930-6.919),1.563(1.154-2.117)].Conclusion:Obesity and high level of TG are dangerous factor of type 2 dia-betes mellitus with NAFLD .
出处 《郑州大学学报(医学版)》 CAS 北大核心 2015年第2期280-282,共3页 Journal of Zhengzhou University(Medical Sciences)
关键词 2型糖尿病 非酒精性脂肪肝 危险因素 type 2 diabetes mellitus non-alcoholic fatty liver disease risk factor
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参考文献10

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二级参考文献10

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