生长抑素治疗粘连性肠梗阻的临床疗效

The Efficacy of Somatostatin in the Treatment of Adhesive Intestinal Obstruction

目的探讨生长抑素治疗粘连性肠梗阻的临床疗效。方法收集2013年1月至2014年5月我院收治的粘连性肠梗阻164例患者资料,将患者随机分为研究组和对照组,各82例。对照组患者给予胃肠减压、肠外营养支持等基础治疗,研究组患者在对照组治疗的基础上给予生长抑素进行治疗,记录两组患者腹痛缓解时间、腹胀缓解时间、肛门排气时间及住院时间,并比较治疗效果。结果研究组患者治疗后腹痛缓解、腹胀缓解、肛门排气及住院时间均明显少于对照组;研究组患者总有效率为95.1%,明显优于对照组的79.3%,差异均有统计学意义(均P<0.05)。结论应用生长抑素治疗粘连性肠梗阻可快速缓解疼痛,并缩短住院时间,提高治疗效果。

Objective To investigate the efficacy of somatostatin in the treatment of adhesive intestinal obstruct-tion.Methods 164 patients with adhesive intestinal obstruction from 2013 January to 2014 May in our hospital patients,randomly divided into study group and control group,each of 82 cases.The control group was treated with decompression,parenteral nutrition support in foundation treatment,study group patients were given somatostatin treatment in the control group patients based on the records of two patients,abdominal pain relief time,abdominal distension relieving time,anal exhaust time and hospital stay,and statistical treatment efficiency.Results The study group patients after abdominal pain relief,distension,anal exhaust and hospital stay were significantly less than the control group;the effective rate of treatment in patients of the study group was 95.1%,significantly higher than 79.3%in the control group,the difference was statistical y significant（P〈0.05）.Conclusion Application of somatostatin in treatment of adhesive intestinal obstruction can quickly relieve pain,shorten the hospitalization time,improve the treatment efficiency.